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Inflammatory disorders news

Inflammatory disorders

Abnormal cellular process implicated in gut inflammation and onset of inflammatory bowel disease

Elevated levels of the key cellular process of apoptosis have been implicated in intestinal inflammation and inflammatory bowel disease (IBD) in a new study from the Quadram Institute.

Immunology

Inflammation: Study explains loss of protective abilities of T cells

Regulatory T cells (Tregs) ensure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies against inflammatory autoimmune diseases such as multiple sclerosis. ...

Immunology

Patients' own cells could be the key to treating Crohn's disease

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.

Immunology

Venoms are sources in the search for new medicines

Animal venoms are the subject of study at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets ...

Diseases, Conditions, Syndromes

New guidelines outline new treatment management for psoriasis

Two new guidelines about the treatment and management of psoriasis have been released by the American Academy of Dermatology, providing physicians with new evidence-based standards of how to treat the disease through the ...

Immunology

Regulating the MS-causing properties of Th17 cells

An international study group led by researchers from Osaka University identifies a protein regulator responsible for inducing the pathogenic properties of Th17 cells, leading to multiple sclerosis and other inflammatory autoimmune ...

Inflammatory disorders

Diagnostic delays common in inflammatory bowel disease

(HealthDay)—Diagnostic delays are common in inflammatory bowel disease, with 68 percent of patients reporting a delay in diagnosis, according to a study presented at the 2019 Crohn's & Colitis Congress, held from Feb. 7 ...

Immunology

Cells that destroy the intestine

Patients affected by the chronic inflammatory bowel diseases morbus Crohn and ulcerative colitis often suffer from flare-ups, which damage intestinal tissue. Despite advances in treating these diseases with medication, associated ...

Alzheimer's disease & dementia

Identification of a central regulator

A new study by LMU researchers shows that the protein ApoE plays a key role in the pathogenesis of diseases associated with chronic inflammation, and identifies a new target for therapeutic strategies against atherosclerosis ...

Cancer

Scientists find link between inflammation and cancer

Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix ...