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Inflammatory disorders news
Medications
Repurposed drug blocks key inflammatory pathways in psoriasis mouse models
A team of skin disease specialists has found that a derivative of the diuretic drug benzamil can be used to block key inflammatory pathways in psoriasis mouse models. In their paper published in the journal Science Translational ...
Dec 12, 2024
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Inflammatory disorders
Asthma more prevalent among children with a rare genetic disorder, study finds
Indiana University School of Medicine researchers have uncovered compelling evidence that children with primary ciliary dyskinesia (PCD), a rare genetic disorder affecting airway function, are significantly more likely than ...
Dec 12, 2024
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Unlocking the clock: The role of the circadian system in inflammatory bowel diseases
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are marked by cycles of immune activation and inflammation that significantly impact patients' lives.
Dec 12, 2024
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Child asthma deaths linked to air pollution, report finds
Of the 54 children who died of asthma between 2019 and 2023, more than 90% were exposed to air pollution levels above World Health Organization (WHO) guidelines, according to a new report published 12 December by the University ...
Dec 12, 2024
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A new way to treat inflammatory skin conditions: Experimental compound targets mast cells
A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published in Science Translational Medicine.
Dec 11, 2024
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Financial hardship linked to asthma medication non-adherence, study shows
Despite a fall in the number of people with asthma over the past decade who say that cost has stopped them taking their meds as prescribed, financial hardship still remains a deterrent for one in six with the condition, suggests ...
Dec 10, 2024
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Benralizumab beneficial for eosinophilic exacerbations of asthma, chronic obstructive pulmonary disease
Benralizumab can be used for the treatment of acute eosinophilic exacerbations of asthma and chronic obstructive pulmonary disease (COPD), according to a study published online Nov. 27 in The Lancet Respiratory Medicine.
Dec 10, 2024
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Trial finds monoclonal antibody therapy improves survival in cancer-associated hyper-inflammatory disorder
Adult patients with newly diagnosed malignancy-associated hemophagocytic lymphohistiocytosis (mHLH)—a rare, aggressive hyperinflammatory condition—who were treated with the first-in-class monoclonal antibody, ELA026, ...
Dec 10, 2024
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We now know a lot more about thunderstorm asthma
Over the past few weeks in Victoria and other parts of Australia, we've been seeing some wild and stormy weather.
Dec 9, 2024
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Engineered immune cells may be able to tame inflammation
When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. But now, scientists at UC San Francisco may have found a more ...
Dec 5, 2024
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Implantable shaking sensor continuously monitors inflammation
Northwestern University scientists have designed a new implantable device that can monitor fluctuating levels of proteins within the body in real time. Inspired by fruit shaking off the branches of a tree, the device comprises ...
Dec 5, 2024
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Research shows dupilumab effective in treatment of children with atopic dermatitis
Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another ...
Dec 5, 2024
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'Game of roulette': Flying with food allergies brings stress, danger
Holiday travel is always stressful, but particularly so for people with food allergies.
Dec 5, 2024
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Study reveals lasting effects of common herbicide on brain health
The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma. Yet for the first time, new research shows even brief contact with a common herbicide can cause lasting damage to the ...
Dec 4, 2024
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New hypothesis on chronic inflammation could lead to advances in disease treatment
A recently published study led by Wayne State University on a new approach to understanding chronic inflammation could lead to new advancements in the treatment of many debilitating medical conditions, including cancer.
Dec 4, 2024
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Mirikizumab proves safe and effective in treating Crohn's disease in Phase III trial
Results of a Phase III study conducted by an international team of researchers reveal that mirikizumab is more effective and has a favorable safety profile with fewer serious adverse events compared to a placebo for individuals ...
An affordable and effective nutritional approach to help reduce inflammation and prevent type 2 diabetes
A team sheds new light on the role of marine-source omega-3 supplementation in treating adipose tissue inflammation and reducing the risk for cardiometabolic diseases like type 2 diabetes.
Dec 2, 2024
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Infants exposed to animals on farms are less likely to develop allergies, study finds
A team of pediatricians, and infectious and inflammatory disease specialists at the University of Gothenburg, working with colleagues from Skaraborg Hospital, all in Sweden, has found a lower incidence of allergies in infants ...
Genomic analysis reveals trigger for cytokine storm in lethal COVID-19
As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause ...
Dec 2, 2024
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Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer
A new study from The Hospital for Sick Children (SickKids) and Institut Curie reveals how stem cells sense and respond to their environment, with implications for inflammatory bowel disease and colorectal cancer.
Dec 2, 2024
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Eating oily fish, fruits and cereals and drinking one pint of beer a week can cut risk of rheumatoid arthritis
Moderate alcohol consumption and a higher intake of fruits, oily fish, and cereals are linked to a lower risk of rheumatoid arthritis, while tea and coffee may be linked to an increased risk, according to new research from ...
Dec 2, 2024
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First new treatment for asthma and COPD in half a century—new study
Every 30 seconds, someone in the world will experience a flare-up of their asthma or chronic obstructive pulmonary disease (COPD) symptoms. For decades, the standard treatment for these potentially life-threatening episodes ...
Nov 29, 2024
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First new treatment for asthma attacks in 50 years
An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%. The findings, published in The Lancet Respiratory Medicine, ...
Nov 27, 2024
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Ultraprocessed foods might help trigger psoriasis
Ultraprocessed foods have been linked to a myriad of health issues, and a new study suggests that the autoimmune skin disease psoriasis might be added to that list.
Nov 27, 2024
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Discovery of mitochondrial mechanism could provide new options for treating inflammatory diseases
Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria. Scientists at the Faculty of Medicine at the University of Freiburg have now shown that a sudden stop in energy ...
Nov 26, 2024
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