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Inflammatory disorders news
Inflammatory disorders
Possible trigger of Crohn's disease discovered: Dysfunctional mitochondria disrupt the gut microbiome
Disruptions of mitochondrial functions have a fundamental influence on Crohn's disease. This connection has now been demonstrated by researchers at the Technical University of Munich (TUM). In a study published in Cell Host ...
Oct 11, 2024
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Inflammatory disorders
AI-supported dermatology for darker skin tones, thanks to new data set
In many countries in Africa, up to nine out of ten children suffer from a skin problem, and there are far too few local dermatologists. Artificial intelligence could help with diagnosis, but needs to be trained with the relevant ...
Oct 11, 2024
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Study shows new drug suppresses systemic inflammatory response syndrome resulting from bypass surgery
Cytokines are regulatory proteins involved in cell proliferation, differentiation, inflammation, and hematopoiesis. An excessive immune response triggered by external viruses can lead to a severe immune reaction known as ...
Oct 10, 2024
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Scientists find potential therapy for fatty liver disease
Metabolic dysfunction-associated steatotic liver disease (MASLD)—previously known as "non-alcoholic fatty liver disease"—affects about 25% of the global population. Its severe form, metabolic dysfunction-associated steatohepatitis ...
Oct 9, 2024
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Adrenaline auto-injectors may not prevent fatal anaphylaxis
Individuals at risk of anaphylaxis—an acute systemic hypersensitivity reaction to an allergen or trigger, typically associated with skin reactions, nausea/vomiting, difficulty breathing, and shock—are often prescribed ...
Oct 9, 2024
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The 'EpiPen' ingredient and how it treats anaphylaxis
The recent approval of a new epinephrine nasal spray gives patients a powerful new way to keep life-threatening allergic reactions at bay.
Oct 8, 2024
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Researchers discover new ways to 'turn off' receptor involved in inflammatory diseases
In 2019, Steven Mansoor, M.D., Ph.D., a physician–scientist at Oregon Health & Science University, and his research team made a groundbreaking discovery: They determined the first complete structure of a protein linked ...
Oct 7, 2024
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Unveiling immune system responses that induce and maintain autoimmune pancreatitis
Autoimmune pancreatitis (AIP) is a clinical condition characterized by inflammation of the pancreas, caused by the body's hypersensitivity to its own proteins. AIP is typically accompanied by other organ inflammations such ...
Oct 7, 2024
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Bimekizumab safe, efficacious over two years for hidradenitis suppurativa
For patients with hidradenitis suppurativa (HS), bimekizumab is safe and efficacious over two years, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. ...
Oct 7, 2024
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Long-term efficacy for lebrikizumab seen in moderate, severe eczema
For patients with moderate-to-severe atopic dermatitis (AD), lebrikizumab has long-term efficacy, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. ...
Oct 5, 2024
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Scientists discover new mechanism controlling T-cells in inflammation
Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as regulatory T-cells, and may serve as potential therapeutic targets to treat inflammatory disorders and ...
Oct 3, 2024
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Scientists use ribosomal tagging to study neuroinfections
Scientists study the functions of microglia by transcriptomics. This method provides dynamic information about genes that are active in the cell in both health and disease states. To do so, they isolate single cells from ...
Oct 2, 2024
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How to get hay fever relief from fall allergies
Autumn is the season of change, with green leaves turning color and temperatures cooling. It's also the season of hay fever, or allergic rhinitis.
Oct 2, 2024
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Study highlights pervasiveness of inflammation in American diet
Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.
Oct 1, 2024
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Addressing health equity in childhood asthma requires engaging affected communities
Systemic racism remains a significant challenge in efforts to address health disparities in childhood asthma. A new American Thoracic Society report provides practical frameworks to begin the research necessary to make real ...
Oct 1, 2024
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Thaumatin, a natural sweetener with anti-inflammatory potential
A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...
Sep 30, 2024
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Home-based phototherapy as effective as office-based for psoriasis
For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual ...
Sep 30, 2024
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Treatment for chronic rhinitis yields significant clinical improvements
Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.
Sep 27, 2024
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A faulty iron hormone in the skin may be the root cause of psoriasis
Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...
Sep 26, 2024
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Signs of developing asthma are evident in the first year of life, health data analysis shows
What factors lead to chronic respiratory disease? Researchers investigated this question using health data from about 780 infants. Their analysis shows that children's risk of developing asthma later in life can be more reliably ...
Sep 26, 2024
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Phase II results suggest targeted therapy is effective for moderate to severe ulcerative colitis
An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative ...
Sep 26, 2024
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Nanobodies help decode the central mechanism of inflammation
The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...
Sep 26, 2024
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New research confirms link between perceived stress and psoriasis relapse
Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented at the European Academy of Dermatology and Venereology (EADV) Congress ...
Sep 26, 2024
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FDA approves Bimzelx for three new indications
The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...
Sep 26, 2024
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Anti-inflammatory drug shows promise in boosting motivation for patients with depression, study reveals
A new study published this week in Molecular Psychiatry by Emory University researchers has revealed a promising new avenue for treating motivational deficits in patients suffering from depression.
Sep 23, 2024
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