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Inflammatory disorders news
Immunology
Immune cell dysfunction in GI tract may lead to onset of inflammatory bowel disease
A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology. The researchers said their discovery provides ...
7 hours ago
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Immunology
Ultrafine bubble showers may help suppress atopic dermatitis
Bubble baths might be soothing soaks, but bubble showers could be the next thing in keeping the skin clean. An Osaka Metropolitan University-led medical research team found that ultrafine bubble showers might help prevent ...
7 hours ago
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Natural fats in human skin could explain why some babies develop eczema
An Australian-first study has found that certain natural fats which exist in the skin of babies, called lipids, are linked to the development of eczema in children.
15 hours ago
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Levodopa may improve motivation in depression linked to high inflammation
A study from Emory University suggests that levodopa, a medication that increases dopamine levels in the brain, may help treat individuals with depression who experience motivational impairments due to high inflammation. ...
Mar 20, 2025
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High-fat diet linked to weakened infection response in mice
A new study published in The Journal of Immunology reveals how a high-fat diet may impair the immune system's ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond ...
Mar 20, 2025
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Scientists discover a type of immune cell that produces defensive 'shields' in the skin
A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Dr. Andrés Hidalgo has discovered a specialized population of neutrophils in the skin that produce extracellular matrix, helping to maintain ...
Mar 19, 2025
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Uncovering barriers to diagnosing and treating vulvar lichen sclerosus
A new study, led by experts at the University of Nottingham, has found the reasons why a vulvar (external female genital) skin condition, linked to cancer, is under diagnosed in general practice.
Mar 19, 2025
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Baricitinib found to be efficacious for hair regrowth in teens with severe alopecia areata
For adolescents with severe alopecia areata (AA), baricitinib is efficacious for hair regrowth, according to a study presented at the annual meeting of the American Academy of Dermatology, held from March 7 to 11 in Orlando, ...
Mar 19, 2025
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Low doses of antibiotic work just as well as higher ones to treat rare type of chronic hair loss, study finds
Small amounts of a common antibiotic and anti-inflammatory drug can curb symptoms where a misplaced immune reaction (e.g., autoimmunity) can cause permanent hair loss, a new study shows. This regimen may also come with fewer ...
Mar 18, 2025
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Maternal diet and infant allergies: The avocado connection
The Hass Avocado Board teamed up with the University of Eastern Finland researchers to examine the relationship between maternal avocado consumption during pregnancy and allergic outcomes in infants. Findings suggest that ...
Global warming linked to increased airway inflammation risk
In a recent, cross-institutional study, researchers report that healthy human airways are at higher risk for dehydration and inflammation when exposed to dry air, an occurrence expected to increase due to global warming. ...
Mar 17, 2025
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Researchers find possible link between medication and unexpected blood clots
Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?
Mar 17, 2025
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Treating chronic inflammatory diseases with JAK inhibitors
Janus kinase (JAK) inhibitors are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. Since their approval, the indications ...
Mar 17, 2025
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Inflammation proteins linked to bone density changes over time
In one of the first studies of its kind, a team of researchers from Keck School of Medicine of USC has found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over ...
Mar 14, 2025
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Topical steroid withdrawal diagnostic criteria defined by researchers
Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in ...
Mar 14, 2025
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Study: Roflumilast cream 0.05% is safe, effective in young children with eczema
Once-daily roflumilast cream 0.05% is safe and effective for atopic dermatitis (AD) in patients ages 2 to 5 years, according to a study published online Feb. 20 in Pediatric Dermatology.
Mar 14, 2025
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Maintenance of low eczema activity seen after about 80 days off tapinarof
Patients with atopic dermatitis (AD) who achieve completely clear skin with tapinarof (Vtama) cream maintain low disease activity after about 80 days off treatment, according to a study presented at the annual meeting of ...
Mar 14, 2025
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Discovery of C-reactive protein's inflammatory pathway in diabetic kidneys offers new treatment avenues
A research team from the School of Chinese Medicine in the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has discovered that C-reactive protein (CRP) can exacerbate kidney inflammation caused by diabetes, ...
Mar 13, 2025
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Semisynthetic bile acid shows promise in reducing gut inflammation
A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation ...
Mar 13, 2025
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Isocyanic acid identified as anti-inflammatory metabolite
In a recent study published in Science Advances, researchers led by Prof. Li Xinjian from the Institute of Biophysics of the Chinese Academy of Sciences have uncovered a novel immunoregulatory function of isocyanic acid (ICA), ...
Mar 13, 2025
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Ivarmacitinib 4 mg, 8 mg efficacious for adults with severe alopecia areata
For adults with severe alopecia areata (AA), ivarmacitinib, a selective Janus kinase 1 (JAK1) inhibitor, at doses of 4 and 8 mg is efficacious and tolerable, according to a study presented at the annual meeting of the American ...
Mar 13, 2025
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Monoclonal antibody significantly reduces nasal polyps and need for surgery in Phase 3 clinical trial
Chronic rhinosinusitis with nasal polyps presents a substantial clinical burden, affecting nasal airflow, olfactory function, and quality of life. Epithelial barrier dysfunction and type 2 inflammatory responses drive disease ...
Cause of post-COVID inflammatory shock in children identified
MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening. Until now, however, the precise cause of the condition was unknown.
Mar 12, 2025
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Routine asthma test more reliable in the morning and has seasonal effects, say doctors
A lung function test used to help diagnose asthma works better in the morning, becoming less reliable throughout the day, Cambridge researchers have found.
Mar 12, 2025
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Blind to the burn: Misconceptions about skin cancer risk in the US
Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs ...
Mar 12, 2025
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