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Inflammatory disorders news
Inflammatory disorders
Potential culprit identified in lingering Crohn's disease symptoms
A study by University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.
20 hours ago
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Medications
FDA expands approval of Vtama to include atopic dermatitis
The U.S. Food and Drug Administration has approved Organon's Vtama (tapinarof) 1% cream for an additional indication -- the topical treatment of atopic dermatitis in adult and pediatric patients aged 2 years and older.
Dec 20, 2024
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Study links alcohol consumption to more severe nut allergy reaction
Findings of a new study into severe allergic reactions offer a sobering warning to people allergic to tree nuts and, more broadly, could lead to quicker diagnoses in emergency care for people with all anaphylactic allergies.
Dec 19, 2024
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Self-guided online treatment can help with atopic eczema
A new study from Karolinska Institutet shows that self-guided cognitive behavioral therapy (CBT) online is as effective as psychologist-led internet-based CBT in reducing the symptoms of atopic eczema. The results, which ...
Dec 19, 2024
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Brain inflammation affects behavior differently in male and female mice
Inflammation in the hippocampus—the brain's memory center—significantly alters motivation and behavior in mice, including food-seeking behavior, with notable differences between males and females, a study reveals.
Dec 19, 2024
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Marine cyanobacteria in the origin of anti-inflammatory molecules with dermatological, cosmetic applications
Inflammation is a biological process through which our body tries to respond to harmful stimuli, through the direct action of the immune system, enzymes and inflammatory mediators. Inflammation of the skin is usually characterized ...
Dec 19, 2024
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Study reveals analgesic and anti-inflammatory properties in Annona squamosa leaves
In Brazil, researchers have identified substances with analgesic, anti-inflammatory, anti-hyperalgesic (against persistent pain) and anti-arthritic activity in the leaves of Annona squamosa, a tree popularly known in the ...
Dec 19, 2024
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FDA approves Nemluvio for moderate-to-severe atopic dermatitis
The U.S. Food and Drug Administration has approved Galderma's Nemluvio (nemolizumab) for the treatment of moderate-to-severe atopic dermatitis in patients aged 12 years and older.
Dec 19, 2024
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Researchers identify key driver of fibrosis in Crohn's disease
Crohn's disease, a type of chronic inflammatory bowel disease (IBD), often causes scar-like tissue to build up in the intestines, termed fibrosis. Over time, increased scar tissue builds up in the intestinal walls, causing ...
Dec 18, 2024
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Cheap inhaler add-on could change asthma care
A device costing just pennies, based on an idea by a University of Manchester Professor to help his son use an inhaler, could be a gamechanger for asthma patients.
Dec 18, 2024
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Brain inflammation may be the reason behind muscle fatigue after infection and injury
Infectious or chronic diseases such as long COVID, Alzheimer's disease and traumatic brain injury can cause inflammation in the brain, or neuroinflammation, that weakens muscles. While scientists are aware of this link between ...
Dec 16, 2024
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Flavonoid powerhouse: Kaempferol's role in taming allergic responses
Allergic diseases such as asthma, atopic dermatitis, and food allergies have been increasing in frequency over the last few years. Food allergies in particular affect millions of people worldwide—this includes allergies ...
Dec 16, 2024
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Repurposed drug blocks key inflammatory pathways in psoriasis mouse models
A team of skin disease specialists has found that a derivative of the diuretic drug benzamil can be used to block key inflammatory pathways in psoriasis mouse models. In their paper published in the journal Science Translational ...
Asthma more prevalent among children with a rare genetic disorder, study finds
Indiana University School of Medicine researchers have uncovered compelling evidence that children with primary ciliary dyskinesia (PCD), a rare genetic disorder affecting airway function, are significantly more likely than ...
Dec 12, 2024
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Unlocking the clock: The role of the circadian system in inflammatory bowel diseases
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are marked by cycles of immune activation and inflammation that significantly impact patients' lives.
Dec 12, 2024
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Child asthma deaths linked to air pollution, report finds
Of the 54 children who died of asthma between 2019 and 2023, more than 90% were exposed to air pollution levels above World Health Organization (WHO) guidelines, according to a new report published 12 December by the University ...
Dec 12, 2024
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A new way to treat inflammatory skin conditions: Experimental compound targets mast cells
A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published in Science Translational Medicine.
Dec 11, 2024
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Financial hardship linked to asthma medication non-adherence, study shows
Despite a fall in the number of people with asthma over the past decade who say that cost has stopped them taking their meds as prescribed, financial hardship still remains a deterrent for one in six with the condition, suggests ...
Dec 10, 2024
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Benralizumab beneficial for eosinophilic exacerbations of asthma, chronic obstructive pulmonary disease
Benralizumab can be used for the treatment of acute eosinophilic exacerbations of asthma and chronic obstructive pulmonary disease (COPD), according to a study published online Nov. 27 in The Lancet Respiratory Medicine.
Dec 10, 2024
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Trial finds monoclonal antibody therapy improves survival in cancer-associated hyper-inflammatory disorder
Adult patients with newly diagnosed malignancy-associated hemophagocytic lymphohistiocytosis (mHLH)—a rare, aggressive hyperinflammatory condition—who were treated with the first-in-class monoclonal antibody, ELA026, ...
Dec 10, 2024
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We now know a lot more about thunderstorm asthma
Over the past few weeks in Victoria and other parts of Australia, we've been seeing some wild and stormy weather.
Dec 9, 2024
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Engineered immune cells may be able to tame inflammation
When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. But now, scientists at UC San Francisco may have found a more ...
Dec 5, 2024
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Implantable shaking sensor continuously monitors inflammation
Northwestern University scientists have designed a new implantable device that can monitor fluctuating levels of proteins within the body in real time. Inspired by fruit shaking off the branches of a tree, the device comprises ...
Dec 5, 2024
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Research shows dupilumab effective in treatment of children with atopic dermatitis
Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another ...
Dec 5, 2024
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'Game of roulette': Flying with food allergies brings stress, danger
Holiday travel is always stressful, but particularly so for people with food allergies.
Dec 5, 2024
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