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Inflammatory disorders news
Immunology
Understanding epigenetic control of antibody responses
Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.
15 hours ago
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Inflammatory disorders
Removing bile acid receptor in gut blocks intestinal inflammation, study shows
Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocks gut inflammation in mice, according to researchers at Children's Hospital Los Angeles. Their findings are published ...
15 hours ago
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Unexplainable chronic itch shows unique blood biomarkers that could eventually lead to new targeted treatments
Millions of patients worldwide suffer from a chronic itching condition with no identifiable cause—a condition known as chronic pruritus of unknown origin (CPUO)—that has no targeted therapies approved to treat it. Many ...
Aug 14, 2024
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Immune cell regulator discovery could lead to treatments for arthritis and severe COVID
The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe COVID 19.
Aug 14, 2024
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Researchers discover new way inflammation impacts cell communication
Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation. The study, recently published in Proceedings of the National Academy of Sciences, ...
Aug 14, 2024
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People with COPD, asthma found to have higher risk of health problems from increased wildfire activity, smoke
Communities impacted by increased wildfire activity and smoke can use a population health-based action plan to help alleviate health risks, particularly for those with chronic obstructive pulmonary disease (COPD) and asthma, ...
Aug 14, 2024
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Season of birth is associated with the development of asthma and allergic rhinitis
Season of birth, and specifically being born in autumn or winter, is associated with allergic rhinitis and asthma in Finland, a new study by the University of Eastern Finland, the University of Helsinki and Helsinki University ...
Aug 14, 2024
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Anti-inflammatory diet could lower your odds for dementia
Eating a healthy diet that dampens inflammation in the body could lower your odds for dementia, especially if you already have heart risk factors, a new Swedish study shows.
Aug 13, 2024
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Dupilumab maintains its effectiveness up to five years in patients with eczema: Study
For patients with atopic dermatitis (AD), dupilumab maintains its clinical effectiveness up to five years and is discontinued by 23.8% of patients, according to a study published online Aug. 7 in JAMA Dermatology.
Aug 12, 2024
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Scabies: What to know about the outbreak of this contagious skin condition in hospitals
Google searches for "NSW scabies outbreak" have spiked over recent days in light of an outbreak of the contagious skin condition in New South Wales.
Aug 11, 2024
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FDA approves first nasal spray to curb anaphylaxis, an alternative to injections
Folks nervous about administering a rescue shot for anaphylaxis finally have a new alternative in a nasal spray.
Aug 10, 2024
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Racial differences identified in frequency of biopsy for psoriasis
There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug 7 in JAMA Dermatology.
Aug 9, 2024
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New findings on CARD14 protein's role in eczema and psoriasis
Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health. Decades of research has shown that a wide range of diseases can occur, or become worse, when ...
Aug 8, 2024
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Study finds sclerotherapy can be successfully used by patients of all skin types, ethnic backgrounds
Chronic venous insufficiency (CVI), which impacts more than 25 million people, includes varicose and spider veins. They occur when the veins become damaged and can't work as they should.
Aug 8, 2024
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Scientists get to the bottom of COVID's worst pediatric complication
Early in the COVID-19 pandemic, some children fought off COVID with few, if any, symptoms, only to go into organ failure a few weeks later.
Aug 7, 2024
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Asthma emergencies spike when allergenic pollen blooms
A new study that tracks how many asthma-related emergency room visits result from pollen in metropolitan areas across Central Texas highlights the importance of knowing local plants and the need for developing science-based ...
Aug 7, 2024
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New research into life-threatening birth defect of the diaphragm
Congenital diaphragmatic hernia (CDH) is a dangerous malformation of the lungs and diaphragm that causes almost a third of affected babies to die from underdeveloped lungs.
Aug 6, 2024
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Rare metabolic disorder can cause liver inflammation
Millions of people worldwide suffer from liver inflammation (hepatitis), an acute or chronic disease with a variety of causes. Liver inflammation frequently occurs in connection with metabolic disorders, for example fatty ...
Aug 6, 2024
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Ultrafine particles linked to over 1,000 deaths per year in Canada's two largest cities
A first-of-its kind study conducted in Canada's two largest cities by McGill-led researchers has linked about 1,100 premature deaths per year to an unregulated air pollutant.
Aug 5, 2024
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Scientists discover mast cells trap and use living neutrophils during allergic reactions
Known for their role in allergic reactions, mast cells have long been recognized as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue ...
Aug 2, 2024
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Study identifies a new disease-inducing mechanism for inflammatory bowel disease
Interleukin-10 (IL-10) is an anti-inflammatory protein that crucially controls intestinal immunity. Children with genetic defects in IL-10, or its receptors, suffer from a severe form of inflammatory bowel disease (IBD) that ...
Aug 2, 2024
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Methotrexate beneficial for reducing pain, stiffness in knee osteoarthritis
For patients with knee osteoarthritis (KOA), methotrexate added to usual medication is associated with a significant reduction in pain and improvement in stiffness and function at six months, according to a study published ...
Jul 31, 2024
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Gen Z perceives atopic dermatitis to be more severe, researchers find
Generation Z (Gen Z) patients present with a higher subjective perception of atopic dermatitis severity than millennial generation patients, according to a study published online July 25 in the International Journal of Dermatology.
Jul 31, 2024
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Psoriasis, psoriatic arthritis tied to higher risk of polyneuropathy
Psoriasis and psoriatic arthritis may be associated with an increased risk of polyneuropathy, according to a study published online June 28 in Muscle & Nerve.
Jul 29, 2024
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Individuals with osteoarthritis are commonly prescribed NSAIDs despite having contraindications
Osteoarthritis affects 600 million people worldwide, making it a leading cause of disability. With no disease-modifying treatments available or on the horizon, oral non-steroidal anti-inflammatory drugs (NSAIDs) are commonly ...
Jul 29, 2024
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