Last update: 39 minutes ago

Cancer drug pushes mutant blood stem cells to become short-lived immune cells

Oncology news

Cancer drug pushes mutant blood stem cells to become short-lived immune cells

The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem cells to become shorter-lived white blood cells, according to a study by Weill Cornell ...

39 minutes ago

Fecal microbiota transplantation may improve immunotherapy-related colitis

Targeting the gut microbiome with fecal microbiota transplantation (FMT) may help cancer patients with immunotherapy-related colitis avoid the need for steroids and other immunosuppressive treatments, according to researchers ...

1 hour ago

Experimental cancer vaccine makes its own oxygen and gives T-cells a boost

When it comes to priorities in life, oxygen tops the list. Humans can go weeks without food and days without water. Take away the ability to breathe, however, and the clock starts ticking within minutes as the brain begins ...

3 hours ago

Investigational immunotherapy nearly doubles overall survival compared with docetaxel in advanced squamous NSCLC

Patients with metastatic squamous non-small cell lung cancer (NSCLC) whose disease progressed following PD-(L)1 inhibitor therapy experienced a median overall survival of 18.5 months with the investigational anti-CTLA-4 antibody ...

2 hours ago

Study identifies distinct outcomes and genomic features in NSCLC with class II and III BRAF alterations

Patients with metastatic non-small cell lung cancer (NSCLC) harboring class II and class III BRAF alterations have distinct clinicopathologic and genomic characteristics, with class III alterations potentially associated ...

3 hours ago

Lower breast, cervical cancer screening seen for adults with disabilities

Individuals with disabilities have a lower prevalence of breast and cervical cancer screening, according to a study published in Cancer.

5 hours ago

PAPILLON trial: Amivantamab plus chemotherapy adds months of survival in rare lung cancer

Final results from the landmark PAPILLON trial, which changed the standard of care for a difficult-to-treat rare form of lung cancer, confirm that amivantamab, when added to chemotherapy, provides durable clinical benefit ...

7 hours ago

AI tool successfully predicts outcomes of immunotherapy in lung cancer

Artificial intelligence (AI) tools can help physicians predict treatment and survival outcomes in patients with advanced non-small cell lung cancer (NSCLC) treated with immunotherapy, according to a new study published in ...

21 hours ago

Magnetic pulses reprogram immune cells to fight breast cancer in preclinical models

Researchers from the National University of Singapore (NUS) have demonstrated an innovative approach for targeted breast cancer therapy using pulsed electromagnetic fields (PEMFs). The NUS team successfully reprogrammed tumor-associated ...

21 hours ago

Hidden proteins in 'non-coding' RNA may offer new clues to cancer progression

Scientists have long believed that large stretches of our genetic material, known as long noncoding RNAs (lncRNAs), help regulate genes but do not produce proteins. A new study by Stav Zok and Professor Michal Linial from ...

20 hours ago

Fifty years after IL-2 discovery, researchers reflect on how it has transformed medicine

A discovery made 50 years ago helped establish the field of human retrovirology, advance understanding of the human immune system and contribute to a revolution in cancer treatment. A new perspective in Science examines that ...

20 hours ago

Promising new option for skin cancer reconstruction uses hydrogel-based template

Researchers at Fox Chase Cancer Center have identified a promising approach to rebuilding tissue after skin cancer surgery that could help some patients avoid more extensive reconstructive procedures.

23 hours ago

Blocking gene boosts T-cell attacks on chronic hepatitis B virus and tumors

A research team led by Professor Zhou Xuyu from the Institute of Microbiology of the Chinese Academy of Sciences (CAS), in collaboration with researchers from Beijing Ditan Hospital and Capital Medical University, has identified ...

Sep 14, 2026

UK-wide rectal cancer study helps improve radiotherapy standards across the country

A major UK-wide cancer study has helped establish new standards for planning and delivering radiotherapy for patients with locally advanced rectal cancer, benefiting patients across the UK, including those in northeast Scotland.

Sep 14, 2026

Data-driven tool to help oncologists identify high-risk periods for metastatic breast cancer patients

Oncologists know that intensive treatment rarely helps patients in their final days, but recognizing when someone is entering that stage is difficult, especially in metastatic breast cancer, where an increasing number of ...

Sep 14, 2026

Researchers identify medulloblastoma molecular groups using noninvasive MRI spectroscopy

Research by Stefan Blüml, Ph.D., and colleagues investigates the use of in vivo proton magnetic resonance spectroscopy (¹H-MRS) to identify medulloblastoma molecular subgroups before surgery, a noninvasive alternative to ...

Sep 14, 2026

Pancreatic tumors use clotting pathway to build immune shields, study finds

Researchers at the Icahn School of Medicine at Mount Sinai have found that small populations of pancreatic cancer cells can create localized immune-protective niches that shield tumors from immune attack. The finding could ...

Sep 13, 2026

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New analysis points to low overdiagnosis in breast cancer screening

When women take part in breast cancer screening, they are informed that screening may detect cancers that would never have caused symptoms or problems during their lifetime. This is known as overdiagnosis.

Sep 13, 2026

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