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Oncology & Cancer news
Oncology & Cancer
World-first guidelines created to help prevent heart complications in children during cancer treatment
The world's first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created.
6 hours ago
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Oncology & Cancer
Targeted therapy momelotinib provides significant symptom and anemia improvements in patients with myelofibrosis
Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according to results from the international ...
14 hours ago
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Researchers map the effects of dietary nutrients on disease
Researchers at the Francis Crick Institute and King's College London have created a tool to predict the effects of different diets on both cancerous cells and healthy cells.
Jan 27, 2023
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One of the causes of aggressive liver cancer discovered: A 'molecular staple' that helps repair broken DNA
Error-correcting mechanisms are very important for cells, because with all the cellular activity constantly going on, malfunctions arise all the time. But when it comes to killing cancer cells, it is in the cells' best interest ...
Jan 27, 2023
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'Collateral damage' from normal cell function may cause mutations that play a role in cancer
The first comprehensive study of somatic mutations in normal human small intestine has been conducted by researchers at the Wellcome Sanger Institute and their collaborators. The findings revealed that an enzyme named APOBEC1 ...
Jan 27, 2023
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How a leukemia hijacks the genes needed by blood stem cells
As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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Breast pain doesn't always mean cancer: When to get a mammogram
While anyone can experience breast pain, don't panic: It's rarely cancer.
Jan 27, 2023
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Could that breast pain be cancer? When to get a mammogram
If you've ever felt pain, tenderness and tightness—maybe even a sharp, stabbing sensation—in your breasts, it's hard not to jump to conclusions. Could it be the "C" word?
Jan 27, 2023
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Researchers identify possible approach to prevent cancer from evolving to resist treatment
A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. ...
Jan 26, 2023
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Immunotherapy combined with targeted therapy for colorectal cancer yields promising outcomes for patients
A new study that used insights from the lab to drive a clinical trial for patients with a difficult-to-treat form of colorectal cancer improved patients' response to treatment and has yielded key insights with broad relevance ...
Jan 26, 2023
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Keys to making immunotherapy work against pancreatic cancer found in tumor microenvironment
A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.
Jan 26, 2023
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An unexpected T cell exhaustion factor driving cancer immunotherapy resistance
A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing ...
Jan 26, 2023
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Loyalty card data could help to identify ovarian cancer symptoms sooner
Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier according to a Cancer Research UK study.
Jan 26, 2023
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'Hard to lose' mutations in tumors may predict response to immunotherapy
Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy. Now, investigators at the Johns ...
Jan 26, 2023
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New findings on therapy-related myeloid cancers
Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, ...
Jan 26, 2023
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Intraventricular immunovirotherapy: A translational step forward
A new research perspective titled "Intraventricular immunovirotherapy; a translational step forward" has been published in Oncotarget.
Jan 26, 2023
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Cancer cells may shrink or super-size to survive
Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered.
Jan 25, 2023
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AI analysis of cancer mutations may improve therapy
Cancer has many faces—no wonder, then, that the range of cancer-causing mutations is huge as well. The totality of such genomic alterations in an individual is what experts call a "mutational landscape." These landscapes ...
Jan 25, 2023
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Bacterium may decrease effectiveness of immunotherapy
Helicobacter pylori is a bacterium that colonizes the stomach lining and is found in more than half of the global population, making it one of the most widespread bacterial infections in the world.
Jan 25, 2023
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Scientists find new marker that predicts early recurrence of breast cancer
A multi-institutional team led by scientists from the Medical College of Wisconsin (MCW) Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who ...
Jan 25, 2023
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