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Oncology & Cancer news
Oncology & Cancer
Researchers discover 'crosstalk' mechanism in two key breast cancer molecules
A significant advance in breast cancer research has uncovered a key mechanism driving cancer invasion and drug resistance. A University of Liverpool study reveals how two critical molecules present in "HER2-positive" breast ...
18 hours ago
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Oncology & Cancer
Algorithm helps guide cancer treatment using circulating tumor DNA from blood samples
A breakthrough by researchers at Peter Mac will allow scientists to detect, analyze and profile cancer tumors in patients via a simple blood test. The Dawson lab at Peter Mac has developed a method that can take circulating ...
18 hours ago
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A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce
Cancer cells are like booming cities without urban planners. They expand quickly, and in doing so, the resulting tumors consume more energy and other resources than they can acquire from nearby blood vessels.
19 hours ago
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Changes in blood cell production over the lifetime could impact leukemia outcomes
Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human ...
18 hours ago
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Molecular 'ZIP code' draws killer T cells to brain tumors
UCSF scientists have developed a "molecular GPS" to guide immune cells into the brain and kill tumors without harming healthy tissue.
21 hours ago
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Researchers map genetic variants associated with pancreatic cancer in Brazilian patients
Pancreatic cancer has recently been included in the list of diseases about which Brazil's National Cancer Institute (INCA) periodically publishes statistics. Although it is not the most frequent type of cancer, its high lethality ...
18 hours ago
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Urine test uses 'zombie' cell proteins for early detection of lung cancer
Scientists in the United Kingdom have created a world-first urine test that could indicate the first possible signs of lung cancer.
22 hours ago
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Auto hematopoietic cell transplant not beneficial for mantle cell lymphoma with undetectable residual disease
Autologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual disease (uMRD), according to a study to ...
18 hours ago
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Imaging technique allows rapid assessment of ovarian cancer subtypes and their response to treatment
An MRI-based imaging technique developed at the University of Cambridge predicts the response of ovarian cancer tumors to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.
Dec 6, 2024
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First look at neuron–tumor connections in brain illuminates formation and spread of gliomas
Every week, Harvard Medical School neuro-oncologist Annie Hsieh treats patients with gliomas—the most common type of brain cancer, including the deadliest, glioblastoma.
Dec 5, 2024
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Possible colon cancer vaccine target uncovered in bacteria
Higher rates of certain cancers in countries, such as the UK, may be linked to two particular strains of bacteria. Targeting these with treatments or vaccines could help reduce the risk of colorectal, bladder, and prostate ...
Dec 5, 2024
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Prevention and screening outpace treatment advances for averting death from five cancer types, study reveals
Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study led by researchers at the National Institutes ...
Dec 5, 2024
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Anticancer drugs could make immunotherapies more effective
An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.
Dec 5, 2024
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Study identifies 'turncoat' cells that fight—and aid—cancer
Yale researchers have made an unexpected discovery—turncoat T cells that help a tumor evade other cancer-fighting immune T cells—in a study of patients living with advanced melanoma.
Dec 5, 2024
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Cell-based immunotherapy shows promise in early clinical trial for breast cancer
A phase one clinical trial exploring a novel cell-based immunotherapy for breast cancer has been published in JAMA Oncology.
Dec 5, 2024
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Opioids interfere with cancer immunotherapy, but another type of drug could help
Opioids are often first-line treatments for cancer-related pain, but they can suppress the immune system and reduce the effectiveness of immunotherapy. New research from the University of Pittsburgh and UPMC Hillman Cancer ...
Dec 5, 2024
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Clinical trial tests new drug to reduce side effect of 'half-matched' stem cell transplants
Adding a new drug to standard care for stem cell transplant recipients may reduce a life-threatening side effect, according to an early-stage clinical trial conducted at Washington University School of Medicine in St. Louis.
Dec 5, 2024
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How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas
When cell growth gets out of control and malignant cells begin to proliferate, cancer can develop in a process known as tumorigenesis. There are always errors in cell division in every body, but sophisticated mechanisms normally ...
Dec 5, 2024
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Recommendations to increase access to whole genome sequencing for children with cancer
Experts have published a series of recommendations for improving equity of access to whole-genome sequencing (WGS) for children with cancer across the U.K.
Dec 5, 2024
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PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis
Among patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence or antagonist-II (PIVKA-II)-based model ...
Dec 5, 2024
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Novel oncolytic immunotherapy shows promise for patients with bladder cancer
A Mayo Clinic Comprehensive Cancer Center researcher will share findings from a late-breaking abstract at the 2024 Society of Urologic Oncology Annual Meeting in Dallas, Dec. 4–6.
Dec 5, 2024
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Research reveals how fructose in diet enhances tumor growth
Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.
Dec 4, 2024
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Cancer risk declines in old age: New research helps explain why
When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning. Age is considered the most important risk factor for cancer. That's because genetic mutations build up in cells over years and ...
Dec 4, 2024
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Unexpected discovery revives abandoned breast cancer treatment
A recent study led by Lund University in Sweden has found that some patients with aggressive breast cancer can be helped by a targeted cancer treatment that had been under development but was shelved. The study is important ...
Dec 4, 2024
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Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer
A new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The method also works for other forms of cancer where resistance may develop. A step is ...
Dec 4, 2024
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