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Oncology & Cancer news

Oncology & Cancer

World-first guidelines created to help prevent heart complications in children during cancer treatment

The world's first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created.

Oncology & Cancer

Targeted therapy momelotinib provides significant symptom and anemia improvements in patients with myelofibrosis

Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according to results from the international ...

Oncology & Cancer

How a leukemia hijacks the genes needed by blood stem cells

As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...

Oncology & Cancer

New findings on therapy-related myeloid cancers

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, ...

Oncology & Cancer

AI analysis of cancer mutations may improve therapy

Cancer has many faces—no wonder, then, that the range of cancer-causing mutations is huge as well. The totality of such genomic alterations in an individual is what experts call a "mutational landscape." These landscapes ...

Oncology & Cancer

Bacterium may decrease effectiveness of immunotherapy

Helicobacter pylori is a bacterium that colonizes the stomach lining and is found in more than half of the global population, making it one of the most widespread bacterial infections in the world.

Oncology & Cancer

New insights into the genetic basis of leukemia

Acute myeloid leukemia (AML) is a malignant disease of the hematopoietic system that originates from immature precursors of red blood cells, platelets and part of the white blood cells. While in healthy people the multiplication ...

Oncology & Cancer

Neuronal molecule makes prostate cancer more aggressive

Prostate cancer is the second most common cancer and the second leading cause of cancer death among American men. Now, researchers have discovered key molecular players that drive prostate cancer to progress into a highly ...

Oncology & Cancer

Lymphoma mutation yields super-competitive immune cells

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional ...

Oncology & Cancer

Structural insights reveal how SPOP protein contributes to cancer

SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely understood. Scientists at St. ...

Oncology & Cancer

Body mass index tied to multiple myeloma survival

Underweight and severe obesity are associated with decreased survival in patients with multiple myeloma (MM), according to a study published online Jan. 12 in the Blood Cancer Journal.

Oncology & Cancer

Military probing whether cancers linked to nuclear silo work

Nine military officers who had worked decades ago at a nuclear missile base in Montana have been diagnosed with blood cancer and there are "indications" the disease may be linked to their service, according to military briefing ...