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Oncology & Cancer news
Oncology & Cancer
Breast, cervical, CRC screening below Healthy People 2020 targets
Receipt of screening tests for breast, cervical, and colorectal cancers was below national Heathy People 2020 targets in 2018, according to research published in the Jan. 14 issue of the U.S. Centers for Disease Control and ...
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Oncology & Cancer
Living macrophage-based drug promotes antitumor immunotherapy
Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of efficacy and safety, such as huge ...
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An unexpected, and novel, target for prostate cancer—our biological clock
Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It's no wonder then that disrupting the clock can wreak havoc on our body. In fact, studies have shown that ...
Jan 15, 2021
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Study sheds light on the longstanding question of why cancer cells get their energy from fermentation
In the 1920s, German chemist Otto Warburg discovered that cancer cells don't metabolize sugar the same way that healthy cells usually do. Since then, scientists have tried to figure out why cancer cells use this alternative ...
Jan 15, 2021
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New computational method detects disrupted pathways in cancer
Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, ...
Jan 15, 2021
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Artificial intelligence tool for reading MRI scans could transform prostate cancer surgery and treatment
Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease ...
Jan 15, 2021
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Scientists demonstrate the role of a protein called ADAMTS1 in rare eye cancer
Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated ...
Jan 15, 2021
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The backlog in mammograms during the COVID-19 pandemic
At its onset, the COVID-19 pandemic severely disrupted medical care, as millions of elective procedures were postponed or canceled. While the volume of many procedures rebounded by the end of July 2020, the disruption caused ...
Jan 15, 2021
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Researchers find NTRK fusions more common than expected in pediatric tumors
In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) ...
Jan 15, 2021
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Tool that predicts if chemotherapy will produce debilitating side effects in older adults
Researchers at City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, have developed a tool that could predict if older adults with early-stage breast ...
Jan 15, 2021
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Scientists develop approach for exploiting cancer's dietary demands
Numerous studies in mice and cancer cells have shown cancer growth can be reduced in response to diets lacking serine. But results have been variable because some cancer cells are efficient in making their own serine, particularly ...
Jan 14, 2021
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Study demonstrates efficacy of new treatment for neurofibromatosis type 1-related tumors
Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Children's Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that ...
Jan 14, 2021
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A new strategy for making blood stem cells healthier
The hematopoietic (blood-forming) stem cells (HSCs) residing in our bone marrow produce all of our blood cells, including key immune cells that protect us from bacteria and viruses. As we age, our HSCs become less efficient ...
Jan 14, 2021
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Researchers discover biochemical pathway that protects cells from ferroptosis
The hallmarks of cancer include rapid cell reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death. To circumvent these negative consequences ...
Jan 14, 2021
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Triggering tumor antiviral immune response in triple negative breast cancer
Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the ...
Jan 14, 2021
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Researchers discover new inhibitor drug combination for rare form of cancer
Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the ...
Jan 14, 2021
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The role of T cells in fighting cancer
New research from CU Cancer Center member Jing Hong Wang, MD, Ph.D., and recent University of Colorado Immunology program graduate Rachel Woolaver, Ph.D., may help researchers develop more effective personalized immunotherapy ...
Jan 14, 2021
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Cancer models created by mechanical engineers offer new insight into tumor growth
As cancer and tumor cells move inside the human body, they impart and are subject to mechanical forces. In order to understand how these actions affect cancer cell growth, spread, and invasion, a team of engineers at Rensselaer ...
Jan 14, 2021
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Bladder cancer—when to use chemotherapy
In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body's immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charité ...
Jan 14, 2021
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Study shows sharp decline in cancer screenings and diagnoses during the first COVID-19 surge
In one of the first studies to examine the impact of the COVID-19 pandemic on cancer diagnoses, researchers at Dana-Farber/Brigham and Women's Cancer Center document a substantial decline in cancer and precancer diagnoses ...
Jan 14, 2021
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