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Oncology & Cancer news
Oncology & Cancer
Clinical trial shows immunotherapy drug pembrolizumab improves outcomes for patients with soft tissue sarcoma
Addition of the immunotherapy drug pembrolizumab to standard of care for patients with advanced soft tissue sarcoma of the limb significantly improved disease-free survival, according to the results of the SU2C-SARC032 clinical ...
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Only half of young cancer patients report a discussion on fertility preservation, researchers find
Only half of people with early-onset cancers reported discussing fertility preservation options prior to their oncology treatments, according to results of a cross-sectional study published Nov. 12 in JAMA Network Open.
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New cancer therapy strategy targets GLUT3 in regulatory T cells to supercharge anti-tumor immunity
Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough in cancer immunotherapy research. Led by Professors Sin-Hyeog Im and Dipayan Rudra, the research ...
7 hours ago
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Glioblastoma: New treatment uses CAR-T cells to attack brain tumors from multiple angles
Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is ...
8 hours ago
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Researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worse
Researchers at City of Hope now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical ...
5 hours ago
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Combination approach shows promise for treating rare, aggressive cancers
A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with ...
9 hours ago
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Study finds 81% of cancer cures touted by TikTok videos are fake
As many as 81% of cancer cures touted by content creators on TikTok are fake, according to new research from City St George's, University of London.
6 hours ago
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Inhibiting METTL3 protein shows promise for high-risk neuroblastoma
Blocking the METTL3 protein can increase sensitivity to chemotherapy in neuroblastoma, according to research from the University of Gothenburg. The study shows how specific RNA modifications affect gene expression in the ...
5 hours ago
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AI tools measure 'immunological fitness' to personalize cancer therapies
Researchers from the Data Science and Artificial Intelligence Institute (DATAI) at the University of Navarra have developed artificial intelligence (AI) models to personalize immune therapies for oncology patients.
7 hours ago
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'Moonlighting' enzymes may lead to new cancer therapies
Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating ...
15 hours ago
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Study identifies new approach to overcome docetaxel resistance in patients with advanced prostate cancer
The treatment landscape for patients with prostate cancer, especially individuals with advanced disease, has dramatically changed in recent years. However, aside from drug or hormonal therapies, other targets to treat prostate ...
5 hours ago
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New blood test offers early detection of drug-induced tissue damage in cancer patients
A team of researchers have applied a novel blood test that can detect early signs of potentially fatal lung damage in cancer patients taking antibody–drug conjugates (ADCs). This breakthrough method aims to offer a safer, ...
5 hours ago
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Treatment target for aggressive leukemia discovered by disrupting its genome organization
Researchers have identified a key weakness in acute myeloid leukemia, offering a promising new strategy to delay the progression of this aggressive blood cancer. The discovery focuses on disrupting the function of a certain ...
9 hours ago
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Medicaid enrollment continuity tied to lymphoma stage at diagnosis
Continuous enrollment in Medicaid was associated with a lower rate of a late-stage lymphoma diagnosis in children and adolescents/young adults (AYAs). However, fewer than half of Medicaid-insured patients in these age ranges ...
10 hours ago
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'Molecular crowbar' protein degradation strategy offers new hope in cancer therapy
In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to identify protein degraders ...
Nov 11, 2024
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Researchers reveal new mechanisms of how fructose promotes colorectal cancer
Fructose, the most common food sweetener, is widely used in processed sugary beverages, candies, and baked goods. Excessive fructose intake is closely associated with metabolic diseases like obesity, diabetes, and fatty liver.
Nov 11, 2024
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Multifunctional antibody shows promise for treating several types of cancer
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine ...
Nov 11, 2024
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Research shows how even one faulty copy of the BRCA1 gene can fuel breast cancer
People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function.
Nov 11, 2024
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New model reveals colorectal tumors originate from multiple cells
In a study published in Nature, researchers led by Prof. Hu Zheng from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, along with their collaborators, demonstrated a new model of ...
Nov 11, 2024
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Researchers uncover new role of mutant proteins in some of the deadliest cancers
Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling ...
Nov 11, 2024
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Study reveal single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia
Researchers from the Tumor Profiler consortium have combined single-cell multi-omics and functional profiling for 21 AML patients to reveal resistance mechanisms to the Bcl-2 inhibitor venetoclax and identify emerging treatment ...
Nov 11, 2024
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Largest T cell clinical trial in solid tumors explores potential for precision immunotherapy
The largest ever clinical trial of T cell therapy for solid tumors has ended, heralding a new era for precision T cell therapy. Led by a Singapore clinician-scientist, the multinational, Phase III VANCE trial demonstrates ...
Nov 11, 2024
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Older adult prostate cancer patients are increasingly being overtreated
Increasing percentages of some older U.S. men with intermediate-risk and high-risk prostate cancers are undergoing treatments that carry risks of side effects that can significantly reduce the quality of life without extending ...
Nov 11, 2024
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Medical physicists develop international radiotherapy dose audits
Medical physicists at the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) have worked with the International Atomic Energy Agency (IAEA) to develop a global radiotherapy audit method.
Nov 11, 2024
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