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Oncology & Cancer news
Oncology & Cancer
Gene-editing therapy shows early success in fighting advanced gastrointestinal cancers
Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results, recently ...
May 2, 2025
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Medical research
Two-week radiotherapy proven as safe and effective as eight-week course for prostate cancer: 10-year follow-up
Prostate cancer is the most commonly diagnosed cancer in men worldwide, accounting for more than 1.4 million new cases each year. For many patients, radiotherapy is a standard treatment option that offers outcomes comparable ...
May 2, 2025
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Sun safety declining in Canada amid rise in skin cancer cases
Despite decades of public health messaging, Canadians are spending more time in the sun and using less sun protection—raising alarms among researchers as melanoma cases continue to climb.
May 2, 2025
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Origins of common lung cancer that affects smokers discovered
The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the ...
May 1, 2025
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Certain surgical gestures during prostate removal linked to better sexual function recovery
After reviewing hundreds of hours of surgical video, a team led by Cedars-Sinai investigators has created a system that links specific steps performed during a surgical procedure to how well patients recover. The study, published ...
May 1, 2025
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Zinc-transporting protein contributes to aggressive growth of brain tumor, researchers find
In a study published Wednesday in the Proceedings of the National Academy of Sciences, University of Oklahoma researchers detail their discoveries about why the brain tumor glioblastoma is so aggressive. Their findings center ...
May 1, 2025
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A new type of super-strong antibody could boost immune systems of cancer patients
Cancer scientists say they have engineered a new type of super-strong antibody which could be used to boost the immune systems of patients fighting the disease.
May 1, 2025
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Lysosome destabilization found to drive iron-dependent cell death in cancer
The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell death, is also necessary ...
May 1, 2025
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FDA-designated orphan drug could increase radiation efficacy in lung cancer
An FDA-designated orphan drug that can target a key vulnerability in lung cancer shows promise in improving the efficacy of radiation treatments in preclinical models, according to a study by UT Southwestern Medical Center ...
May 1, 2025
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More men with prostate cancer are avoiding unnecessary surgery
Prostate cancer is a leading cause of cancer-related death among men in the United States. Despite this, widespread adoption of prostate cancer screening has been controversial. Many primary care doctors worry that screening ...
May 1, 2025
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Enzyme PRMT5 found to drive chemotherapy resistance in ovarian cancer
Northwestern Medicine scientists have identified a key driver of chemotherapy resistance in advanced ovarian cancer, according to a study published in the Journal of Clinical Investigation.
May 1, 2025
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New research guides treatment regimen for aggressive blood cancer
Relapsed/refractory (R/R) mature T and natural killer (NK)-cell lymphomas (TNKL) are aggressive blood cancers often resistant to frontline therapies. A team of Mass General Brigham researchers found that patients with these ...
May 1, 2025
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Rare cancer synovial sarcoma reduced using plasma-activated medium
Plasma-activated medium (PAM) shows tumor-fighting effects against the rare form of cancer known as synovial sarcoma, an Osaka Metropolitan University-led research team has found.
May 1, 2025
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Single-cell atlas reveals hidden patterns of differentiation in acute myeloid leukemia
Princess Margaret Cancer Center at University Health Network-led researchers constructed a detailed single-cell atlas of human blood development, improving understanding of leukemia formation and enabling a more precise classification ...
Black and Hispanic children with high-risk neuroblastoma have worse outcomes despite standardized treatment
Black and Hispanic children with high-risk neuroblastoma experience worse survival outcomes than their white peers, even when treated in frontline clinical trials, according to a study led by a UT Southwestern Medical Center ...
Apr 30, 2025
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Single DNA mutation disrupts key tumor-suppressing pathways, elevating blood cancer risk
Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.
Apr 30, 2025
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PBAF chromatin may explain melanoma spread to the brain
Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in Molecular Cell, highlights ...
Apr 30, 2025
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Old drug, new tricks: Why an anti-psychotic could help treat brain cancer
New research from SAHMRI and Flinders University has shed light on how the decades-old antipsychotic drug, trifluoperazine (TFP), works against glioblastoma (GBM), the most aggressive form of brain cancer.
Apr 30, 2025
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'Game-changer' clinical trial launches for Australia's second-deadliest cancer
A world-first clinical trial launched in Melbourne is being hailed as a "game-changer" for its potential to revolutionize the way people with bowel cancer are treated.
Apr 30, 2025
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Identifying noncancer risks among Japanese female breast cancer survivors
Breast cancer is the most common cancer among women in several countries around the world, including Japan, where 1 in 9 women has the risk of developing the disease. In recent years, early detection and advancements in treatment ...
Apr 30, 2025
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Lower screening age calls for more tailored bowel cancer surveillance
Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes—but it will also increase the burden on an already struggling health care ...
Apr 30, 2025
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Universal screening approach achieves a comparable detection rate of lung cancer
Research led by Professors Jianxing He and Wenhua Liang from the First Affiliated Hospital of Guangzhou Medical University and the National Clinical Research Center for Respiratory Disease, focusing on lung cancer screening ...
Apr 30, 2025
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Novel CAR-T therapy achieves positive results in a high proportion of patients with a refractory type of lymphoma
Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 ...
Apr 29, 2025
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Computational analysis clarifies cancer risk for families with genetic variants
QIMR Berghofer-led research has shown that new advanced computational prediction tools can improve the accuracy of genetic testing for families affected by an inherited condition that significantly increases their risk of ...
Apr 29, 2025
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Exercise can counter detrimental effects of cancer treatment, review suggests
Exercise can counter the detrimental effects of cancer treatment, such as heart and nerve damage and brain fog, suggests an overarching review of the existing pooled data analyses of the most recent research, published online ...
Apr 29, 2025
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