A form of lung cancer, which is found in about 10%–15% of Western patients and 40%–50% of Asian patients, is driven by a mutation in the epidermal growth factor receptor (EGFR) gene. Gefitinib is a go-to drug that shuts down ...
Stopping a cancer cell from dividing does not necessarily make it harmless. Chemotherapy can leave behind living, senescent cells. These 'zombie' cells can release inflammatory signals, helping tumors resist treatment. Drugs ...
Experts from the University of Nottingham have discovered how a common genetic mutation disrupts the positioning of a key protein during cell division, revealing a new mechanism behind acute myeloid leukemia and a potential ...
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When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. Among those are IDH-mutant gliomas, a group of brain tumors that invariably recur despite ...
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Cancer cachexia has long been one of oncology's most stubborn unsolved problems. This severe, uncontrollable wasting affects roughly half of all cancer patients. It makes treatment harder to tolerate, erodes a person's quality ...
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Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.
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A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute ...
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Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This circular DNA frequently carries oncogenes—genes that promote cancer. Researchers have long sought vulnerabilities ...
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Contrary to popular belief, the postmenopausal ovary is not defunct. In a new study of ovaries from 28 women, scientists at Northwestern University and the Buck Institute for Research on Aging found that in the decades well ...
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A team of scientists in Norway has found evidence for a new mechanism for the development of cancer in children: They seem to produce an unusual amount of aberrant antibodies against the building blocks that make up the DNA ...
23 hours ago
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