Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does, and how the two may be involved in ...
13 hours ago
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89
The RAF protein could be a therapeutical target to treat tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine ...
14 hours ago
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52
A massive analysis of the entire genomes of 2,658 people with 38 different types of cancer has identified mutations in 179 genes and gene regulators as "drivers"—variations in DNA sequences that lead to the development ...
15 hours ago
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38
Researchers have found drug fragments, which could help improve our understanding of the function of a key cancer protein and ultimately lead to new drug treatments.
17 hours ago
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57
Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed ...
Feb 19, 2020
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104
A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. This mechanism, the study ...
Feb 19, 2020
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39
Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence. This pathway may be modulated during senescence-inducing chemotherapy ...
Feb 19, 2020
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60
An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer.
Feb 19, 2020
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26
A multi-institutional group of researchers led by Children's Hospital of Philadelphia (CHOP) has linked a strong cancer driver gene to changes in proteins that regulate alternative splicing. The researchers created new computational ...
Feb 17, 2020
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102
Scientists have a developed a new technique to decipher how millions of individual cells are communicating with each other in miniature tumours grown in the lab, known as organoids, according to new research published in ...
Feb 17, 2020
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