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Pulmonary medicine news
Study identifies estrogen receptor as key protector of the right heart in pulmonary hypertension
Researchers at National Jewish Health have identified a key way estrogen receptor alpha (ERα) helps protect the right side of the heart in pulmonary hypertension. The preclinical findings reveal that ERα preserves the survival ...
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Working with engineered stone countertops can lead to silicosis lung disease
There are substantial health hazards to working with engineered stone countertops, as an article on silicosis, a disease caused by inhaling silica crystals, illustrates in a study appearing in the Canadian Medical Association ...
Sep 21, 2026
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How a single viral protein hijacks immune cells to supercharge COVID-19 infection
In the sickest COVID-19 patients, SARS-CoV-2 doesn't just cause severe damage by directly infecting airway cells. The virus can also trigger hyperinflammation—a cycle in which immune cells themselves become infected, stop ...
Sep 18, 2026
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Rare inherited EGFR mutation linked to dramatically increased lung cancer risk
A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research ...
Sep 17, 2026
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Wildfire smoke may be more harmful than other air pollution, two studies find
As climate change drives more frequent and intense wildfires, researchers at the Icahn School of Medicine at Mount Sinai have published two large-scale studies showing that wildfire smoke may pose greater health risks than ...
Sep 17, 2026
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How new artificial lung technology could change the game for chronic lung disease
Long-term medical treatment for chronic lung disease has stumped doctors and scientists for years. Now, researchers from Carnegie Mellon University have created new artificial lung technology that could drastically change ...
Sep 17, 2026
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New test could dramatically speed diagnosis of hard-to-detect lung infections
A little-known chronic lung disease is silently emerging as a growing public health threat in the U.S. and around the world. Nontuberculous mycobacteria—a group of 200 known environmental bacteria found in soil and water, ...
Sep 16, 2026
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Hot, dry weather can make you cough more—salty air might help
UNC School of Medicine researcher Brian Button, Ph.D., professor of biochemistry and biophysics, and collaborators have identified how extremely dry air during heat waves can make the airways more sensitive and more likely ...
Sep 15, 2026
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Sleep app tracks link between air pollution and a bad night's sleep
Has your partner ever woken you up at night with their coughing? Has your coughing ever woken them up? New research suggests it could be due to air pollution levels in your area, even if those levels are low.
Sep 15, 2026
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PAPILLON trial: Amivantamab plus chemotherapy adds months of survival in rare lung cancer
Final results from the landmark PAPILLON trial, which changed the standard of care for a difficult-to-treat rare form of lung cancer, confirm that amivantamab, when added to chemotherapy, provides durable clinical benefit ...
Sep 15, 2026
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IASLC tumor budding grade identifies high-risk patients with resected lung squamous cell carcinoma
A newly proposed International Association for the Study of Lung Cancer (IASLC) tumor budding–based grading system successfully identified patients with resected lung squamous cell carcinoma (SqCC) at higher risk of poor ...
Sep 15, 2026
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Investigational immunotherapy nearly doubles overall survival compared with docetaxel in advanced squamous NSCLC
Patients with metastatic squamous non-small cell lung cancer (NSCLC) whose disease progressed following PD-(L)1 inhibitor therapy experienced a median overall survival of 18.5 months with the investigational anti-CTLA-4 antibody ...
Sep 15, 2026
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Mobile CT lung cancer screening expands access for underserved populations in Brazil
Mobile low-dose computed tomography (LDCT) screening can reach high-risk and socially vulnerable populations in resource-limited settings, according to initial results from the Third Brazilian Early Lung Cancer Trial (BRELT3) ...
Sep 15, 2026
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Bacteria in the airway may shape air pollution health risk
Air pollution is linked to different risks of bacterial pneumonia, sepsis and meningitis, depending on the bacterial subtype a person carries, new research suggests.
Sep 14, 2026
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Dust mites plus silica can trigger a pathway to steroid-resistant lung inflammation
Inflammation associated with asthma and other allergic airway diseases can be significantly worsened by exposure to both house dust mite allergens and crystalline silica, according to a new study published in the journal ...
Sep 14, 2026
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Zidesamtinib demonstrates 93% response rate in ROS1-positive lung cancer
New results from the global phase 1/2 ARROS-1 trial showed clinically meaningful activity with zidesamtinib in patients with advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC) who had not previously received ...
Sep 13, 2026
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Amivantamab-chemotherapy demonstrates longest overall survival reported for lung cancer with EGFR mutation
Results from the phase 3 PAPILLON study show that first-line amivantamab plus carboplatin-pemetrexed (amivantamab-chemotherapy) was associated with numerically longer overall survival compared with chemotherapy in patients ...
Sep 13, 2026
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Update shows sustained overall survival benefit with adjuvant osimertinib in resected EGFR-mutated lung cancer
An exploratory 8-year landmark update from the Phase III ADAURA trial showed that adjuvant osimertinib continued to provide a long-term overall survival benefit for patients with completely resected, EGFR-mutated stage IB–IIIA ...
Sep 13, 2026
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First-line trastuzumab deruxtecan significantly improves progression-free survival in HER2-mutant lung cancer
First-line treatment with trastuzumab deruxtecan (T-DXd) significantly improved progression-free survival compared with pembrolizumab plus platinum-based chemotherapy in patients with advanced or metastatic HER2-mutant non-small ...
Sep 13, 2026
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Wound-healing peptides curb bacterial colonization in cystic fibrosis airway models
Cystic fibrosis, one of the most common genetic diseases in Switzerland, promotes chronic bacterial infections by impairing the protective barrier of the airways. Scientists at the University of Geneva (UNIGE) have discovered ...
Sep 12, 2026
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Ivonescimab significantly improves overall survival versus pembrolizumab in advanced lung cancer
Ivonescimab significantly prolonged overall survival compared with pembrolizumab as first-line treatment for patients with PD-L1-positive advanced non-small cell lung cancer (NSCLC), according to a prespecified interim analysis ...
Sep 12, 2026
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Trial shows risvutatug rezetecan significantly improves overall survival in relapsed small-cell lung cancer
Results from the randomized Phase III ARTEMIS-008 trial show that risvutatug rezetecan (Ris-Rez), a B7-H3-directed antibody-drug conjugate, significantly improved overall survival compared with topotecan in patients with ...
Sep 12, 2026
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Tam-Peli extends survival by nearly four months in relapsed small-cell lung cancer
The phase 3 TAISHAN-302 trial found that tambotatug pelitecan (Tam-Peli, YL201), a novel anti-B7-H3 antibody-drug conjugate, significantly improved overall survival, progression-free survival and objective response rate compared ...
Sep 12, 2026
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Subcutaneous tarlatamab shows favorable safety profile and antitumor activity in extensive-stage small cell lung cancer
Subcutaneous administration of tarlatamab was well tolerated and demonstrated preliminary antitumor activity in patients with previously treated extensive-stage small cell lung cancer (ES-SCLC), according to findings from ...
Sep 12, 2026
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Pumitamig plus elfetabart drozuntecan shows encouraging early activity in small cell lung cancer
The investigational combination of pumitamig and elfetabart drozuntecan (elfe-D) demonstrated a manageable safety profile and encouraging early antitumor activity in patients with small cell lung cancer (SCLC), according ...
Sep 12, 2026
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