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HIV & AIDS news
Medications
Lenacapavir reduces viral load in multidrug-resistant HIV-1 infection
Patients with multidrug-resistant HIV-1 infection receiving the capsid inhibitor lenacapavir have a greater reduction in viral load than those receiving placebo, according to a study published in the May 12 issue of the New ...
May 12, 2022
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Antibody dependent cellular cytotoxicity may help prevent HIV transmission from mother to child during breastfeeding
According to new research from Boston Medical Center, the antibody function known as antibody dependent cellular cytotoxicity (ADCC) and the ADCC sensitivity of HIV strains may influence the transmission of HIV from mother ...
Apr 20, 2022
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Antibody therapy controls HIV for months in new clinical trial
Antiretroviral therapy has made HIV a manageable condition, but it does not eliminate the virus from the body—and most regimens are expensive and require a pill every day, for the rest of the patient's life.
Apr 19, 2022
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The antibodies of 'post-treatment HIV controllers'
A very small percentage of people with HIV-1, known as "post-treatment controllers" (PTCs), are able to control their infection after interrupting all antiretroviral therapy. Understanding the fundamental mechanisms that ...
Apr 14, 2022
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Sequencing HIV proviruses from people on antiretroviral therapy using droplet-microfluidics
The infection of human immunology viruses (HIV) occurs by integrating its genome into infected cells to enter an inactive state of reversible latency that evades anti-retroviral therapy. The capacity to sequence such a provirus ...
Protease inhibitors safer than previously thought for pregnant women with HIV
University of Oxford researchers assessed evidence from 34 studies, involving more than 57,000 pregnant women with HIV, and found that protease inhibitor-based antiretroviral therapies significantly increased the risk of ...
Apr 12, 2022
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New approach for delivery of anti-HIV antibody therapy shows promise in phase I clinical trial
Since the first reports of HIV infection in the early 1980s, multiple clinical trials have tested potential vaccines against the virus, but unfortunately, HIV has numerous defense mechanisms that prevent a person's immune ...
Apr 11, 2022
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Climate change reduces HIV treatment adherence in Africa
Droughts caused by climate change can have an impact on HIV treatment, according to a new study led by researchers at Brighton and Sussex Medical School (BSMS), Africa Health Research Institute (AHRI) and the University of ...
Apr 11, 2022
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HIV pre-exposure prophylaxis works but needs regular testing
HIV pre-exposure prophylaxis (PrEP) is a prevention strategy which includes the regular or event-driven use of antiretroviral medication to prevent HIV infection in adults. Several clinical trials demonstrated that PrEP effectively ...
Apr 07, 2022
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Antibiotic and antiretroviral drug effects on breast milk explored for mothers living with HIV
Infants carry a vast assemblage of bacteria, viruses and fungi in their guts. Combined, these microbes make up a complex ecology known as the gut microbiome, which plays a major role in health and disease throughout life. ...
Apr 06, 2022
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CRISPR and HIV: New technique in human blood unveils potential paths toward cure
Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus ...
Apr 01, 2022
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Researchers identify sustainable source of immunodeficiency virus-resistant immune cells
Genetic engineering can make immune cells resistant to infection with human or monkey (simian) immunodeficiency virus (HIV and SIV, respectively). Recently, treatment with HIV-resistant immune cells has given encouraging ...
Mar 31, 2022
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Uncovering the HIV life cycle
Though it has been eclipsed lately by SARS-CoV-2, there is another global epidemic still threatening people: HIV/AIDS. According to UNAIDS, a United Nations initiative, some 38 million people worldwide are currently infected ...
Mar 29, 2022
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New study reveals why HIV remains in human tissue even after antiretroviral therapy
Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering ...
Mar 25, 2022
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HIV hides within immune system's 'police stations'
Antiretroviral therapy (ART) is highly effective at controlling HIV infections, but the virus never completely goes away. Instead, it hides in roughly one in every 1 million immune cells.
Mar 23, 2022
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Blood test figures in cancer risk for people with HIV
In the clinical care of people living with HIV, various types of blood cells are routinely counted to assess the immune system, among them CD4+ cells, or T helper cells, and CD8+ cells, or cytotoxic T cells.
Mar 18, 2022
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Researchers demonstrate high prevalence of cancer among men living with HIV
Researchers with Case Western Reserve University have found that there are nearly twice as many men with cancer among men living with HIV (MLWH) compared to men who do not have the human immunodeficiency virus. The rates ...
Mar 17, 2022
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Study shows mRNA vaccine technology can be used for HIV vaccines
Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.
Mar 16, 2022
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Trial of innovative HIV vaccine using mRNA technology enrolls first participant
The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna. The study evaluates the safety of and immune responses ...
Mar 14, 2022
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