Researchers discover potential target to treat severe anemia in patients unresponsive to standard treatments
Red blood cells are the most abundant cells in the body. It has long been known that when red blood cells break down or anemia occurs due to bleeding, the hormone erythropoietin (EPO) increases, leading to the proliferation ...
6 hours ago
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Study warns high serum magnesium levels in septic patients linked to increased mortality
Sepsis is one of the most common life-threatening conditions in intensive care units, with approximately 48.9 million cases reported worldwide in 2017, accounting for 19.7% of total global mortality. Given the severity of ...
5 hours ago
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Ground squirrel study points to potential development of a cataract drug
Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age. ...
Sep 18, 2024
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Molecular pathway discovery points to a way to modulate scarring in spinal cord injury
After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves from regenerating, impeding ...
Sep 18, 2024
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New study casts doubt on loneliness as a cause of many diseases
A team of medical researchers has found via analysis of patient data from multiple sources, that many diseases that have been thought attributable to loneliness are more likely due to other causes. The work is published in ...
Brown fat: How cells generate heat by burning calories
Special fat cells known as brown adipocytes help maintain body temperature by converting calorie-rich nutrients into heat. This protects us from gaining excess weight and from metabolic disorders.
Sep 16, 2024
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Addressing challenges to clinical translation of biomarkers of aging tools
Biomarkers of aging are an emerging class of tools that allow for quantitative assessment of biological age and the impact of interventions targeting the aging process. These tools are proving to be transformative in the ...
Sep 16, 2024
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Metformin found to reduce organ aging in male monkeys
A team of biologists affiliated with multiple institutions in China, working with a colleague in the U.S., has found that giving cynomolgus monkeys the diabetes drug metformin can reduce aging in multiple organs, including ...
Researchers discover new target for treating heart failure: Protein kinase N
As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart failure. A group from the ...
Sep 13, 2024
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3D organoid culture method can generate large numbers of muscle cells in vitro
Harvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in vitro.
Sep 12, 2024
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Researchers uncover how cells deal with formaldehyde toxicity during growth and aging
AMeD syndrome is a severe genetic condition found in children that presents with accelerated aging, global developmental delay and bone marrow failure, progressing to myelodysplastic syndrome and acute myeloid leukemia.
Sep 12, 2024
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Placebos can alleviate chronic back pain, even when patients know they're placebos
Honestly prescribed placebo treatments for chronic back pain (CPB) led to significant improvements in pain alleviation with lasting results, according to a new study out today in JAMA Network Open.
Sep 11, 2024
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Stress-induced events jumpstart sperm performance once the event has passed, research reveals
A study led by researchers at the University of Colorado Anschutz Medical Campus reveals that stress-induced changes in sperm motility occur after a stressful event, rather than during it and improves sperm performance. The ...
Sep 11, 2024
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Regulatory T cells enhance tissue healing in mouse model
Investigators are constantly aiming to identify new therapeutic approaches for regenerative medicine. Recent strategies have focused on harnessing the power of the body's own tissue healing and repair mechanisms, including ...
Sep 11, 2024
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Implanting aged oocytes in young follicles can produce rejuvenated eggs, researchers find
A multi-institutional team of ovarian biologists and other reproductive specialists reports that putting an oocyte from an older mouse into the follicle of a young mouse can rejuvenate the oocyte, allowing for the release ...
Clinical trials of new cancer drugs may inappropriately exclude people of African/Middle Eastern descent
Many clinical trials of new cancer drugs may be inappropriately excluding some people with "Duffy-null phenotype," a trait found predominantly in people of African or Middle Eastern descent, researchers at Dana-Farber Cancer ...
Sep 11, 2024
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US-based researchers win $1 million prize for their work on face recognition
Four researchers working in the United States are sharing a $1 million prize from a Portuguese foundation for their work on how the human brain distinguishes faces, shapes and colors.
Sep 11, 2024
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New study explores challenges and opportunities for cancer research
Cancer cells are driven by the same imperative guiding all living things: to grow, survive and reproduce. Although cancer's evolutionary underpinnings have been recognized since the 1950s, clinicians have been slow to apply ...
Sep 11, 2024
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'Cuddle hormone' oxytocin may provide pain relief and help curb harmful opioid use, study suggests
In the midst of America's growing opioid crisis, a much healthier alternative to long-term pain management is emerging—one affectionately known as "the cuddle hormone," or oxytocin.
Sep 11, 2024
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New study shows that chronic neurodegeneration can be prevented after traumatic brain injury
Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with chronic neurodegeneration and related impairments due to TBI. In addition ...
Sep 10, 2024
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Researchers identify cellular pathways whose dysregulation leads to acne lesions
Acne is the most common dermatological condition worldwide and has been shown to have significant psychological effects on sufferers, especially teenagers.
Sep 10, 2024
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Study reveals how insulin-producing cells work together to respond to metabolic demands
Scientists have revealed how a population of insulin-producing cells (IPCs) in the fruit fly brain works together to produce a concerted response to metabolic demands and internal state changes.
Sep 10, 2024
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Abdominal fat linked to widespread chronic pain, especially in women
Excess abdominal fat is associated with widespread chronic pain, particularly in women, finds the first study of its kind, published in the open access journal Regional Anesthesia & Pain Medicine.
Sep 10, 2024
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