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N-cadherin triggers neural stem cell differentiation: Discovery shows potential for brain aging and disease therapies

Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes affected by aging or neurodegenerative diseases.

Medical research

For advances in treating ACL injuries, look to dogs

Even after surgery, injuries to the anterior cruciate ligament (ACL) often lead to chronic pain and reduced mobility, with limited options for treatment. New research suggests that advances in knowledge and therapeutics may ...

Medical research

Exploring the effect of oxidizing compounds on melanoma cells

Melanoma is the most aggressive form of skin cancer. Although less common, it is the most serious due to its high potential for metastasis. Despite the health benefits of sunlight, prolonged exposure to ultraviolet rays is ...

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Crafting artificial skin from fish-based hydrogels

The skin is the largest organ in the human body. It makes up about 15% of our body weight and protects us from pathogens, dehydration and temperature extremes. Skin diseases are therefore more than just unpleasant—they ...

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FDA announces plan to phase out some animal testing

The U.S. Food and Drug Administration announced it is shifting away from animal testing in the development of monoclonal antibody therapies and other drugs, favoring more effective, human-relevant methods.

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New CONSORT reporting guidelines released

An updated set of guidelines to improve transparency and clarity in the reporting of randomized controlled trials have been published. The CONSORT (Consolidated Standards of Reporting Trials) 2025 statement provides a minimum ...

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New strategy may enable cancer monitoring from blood tests alone

A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a ...

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Research reveals gender gap in trauma whole blood transfusions

Traumatically injured women are considerably less likely to receive whole blood transfusions within the first four hours of injury compared to men, despite whole blood being associated with reduced mortality in both women ...

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VA research stalls under hiring freeze

One hundred years ago, scientific research began at the U.S. Department of Veterans Affairs, eventually yielding discoveries like the implantable pacemaker, the nicotine patch and the concept of a CT scan.

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Starch-based microplastics linked to health issues in mouse study

Wear and tear on plastic products releases small to nearly invisible plastic particles, which could impact people's health when consumed or inhaled. To make these particles biodegradable, researchers created plastics from ...

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Research on multiple sclerosis wins 'Oscars of science'

An American neurologist and an Italian epidemiologist whose work revolutionized the treatment of multiple sclerosis on Saturday won a prestigious Breakthrough Prize, the award nicknamed the "Oscars of science."

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Cannabis terpenes shown to prevent pain in new study

It's common knowledge that many use cannabis and natural products to treat pain symptoms, especially as the nation reckons with the deadly consequences of the opioid epidemic. But what if aromatic compounds in cannabis could ...

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Nanoparticles extend glioblastoma survival in phase one trial

Despite decades of research to develop effective treatments, the median survival for glioblastoma—the most common malignant primary brain tumor in adults—is just 15–18 months after diagnosis. One reason for this grim ...

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New study validates lower limits of human heat tolerance

A study from the University of Ottawa's Human and Environmental Physiology Research Unit (HEPRU) has confirmed that the limits for human thermoregulation—our ability to maintain a stable body temperature in extreme heat—are ...

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Barriers to including non-English speakers in research explained

Health researchers omit including speakers of languages other than English (LOE) in their studies due to lack of training, challenges securing interpreter services, budget constraints and other barriers, according to a new ...

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Study reveals how Chagas parasite invades human cells

Researchers from Auburn University, in a landmark collaboration with Brazil's Oswaldo Cruz Foundation (FIOCRUZ), the world's leading research institution on Chagas Disease, have published a significant study in the journal ...