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Researchers identify proteins that could predict liver transplant rejection

Northwestern University scientist have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care.

Medical research

'Cell atlas' of brain vasculature connects stroke with novel immune cells

In work that will enhance the study of such diseases as stroke and dementia, researchers at UC San Francisco have cataloged all the cells that form the blood vessels of the human brain, along with their locations and the ...

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Researchers regrow frog's lost leg

For millions of patients who have lost limbs for reasons ranging from diabetes to trauma, the possibility of regaining function through natural regeneration remains out of reach. Regrowth of legs and arms remains the province ...

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Gene expression could ring early kidney disease alarm

Biomedical engineers at Duke University have developed a method to study how key cells in the kidneys become injured and deformed. The new model has revealed a significant mechanism behind severe kidney disease and pointed ...

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Rapid eye movement sleep helps protect against predator attack

Rapid eye movement (REM) sleep brings about brief but periodic awakenings. In 1966, Dr. Frederick Snyder reported the "sentinel" function of REM could help animals prepare a fight or flight response against potential predator ...

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One in four people who had COVID-19 symptoms do not test

Research found older age groups were most likely to not recognize they had a key symptom that qualified for a COVID-19 test. These symptoms are fever, cough, or change or loss of smell/taste. The findings suggest there is ...

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Supplement appears to boost muscle, mitochondria health

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans. New research suggests that the supplement, urolithin A, may help improve or prolong muscle ...

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TV watching linked with potentially fatal blood clots

Take breaks when binge-watching TV to avoid blood clots, say scientists. The warning comes as a study reports that watching TV for four hours a day or more is associated with a 35 percent higher risk of blood clots compared ...

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'Decoy' protein works against multiple SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers ...

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Calcium: Important not just for your bones but also for your heart

Researchers from Osaka University found a previously unknown gene mutation that can cause an incurable heart condition called dilated cardiomyopathy. This gene, BAC5, is important for the movement of calcium ions in the heart ...

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International team advances research on muscle health

An international team, led by University of Ottawa Faculty of Medicine researchers, has published findings that could contribute to future therapeutics for muscle degeneration due to old age, and diseases such as cancer and ...

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Ethnic disparities seen in enrollment for a clinical trial​

(HealthDay)—In the Bronchiolitis Follow-up Intervention Trial (BeneFIT) setting, physicians more often determined that Hispanic patients were not appropriate for as-needed follow-up and excluded them from the trial, according ...

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Researchers identify novel pathways responsible for liver cancer

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year. HCC ...

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Neutral mutants can prevail in gut microbiota, enhancing diversity

Scientists at EPFL and Sorbonne propose a new model of the diversity and evolution of gut bacteria that shows how the gut environment helps neutral mutations become prevalent, with significant potential implications on health ...

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The circadian clock in heart failure

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team at Baylor College of Medicine and collaborating ...

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Jigsaw-shaped peptide solves tissue regeneration puzzle

Recreating native physiological processes in manmade materials imitating the biological structures involved in wound healing has proved to be a lasting challenge. The main problems are modeling the appropriate functions that ...

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The vital need for animal testing

ETH Zurich and the other Swiss universities are committed to reducing the stress and suffering experienced by laboratory animals. However, an outright ban on animal testing—being put to the vote in a popular initiative ...

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Regrowing knee cartilage with an electric kick

UConn bioengineers successfully regrew cartilage in a rabbit's knee, a promising hop toward healing joints in humans, they report in the 12 January issue of Science Translational Medicine.

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New cloud-based platform opens genomics data to all

Harnessing the power of genomics to find risk factors for major diseases or search for relatives relies on the costly and time-consuming ability to analyze huge numbers of genomes. A team co-led by a Johns Hopkins University ...