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Blood may hold clues to some of COVID-19's most mysterious symptoms

The most severe cases of COVID-19 begin with leaky blood vessels. Breaches in the vascular system cause inflammation and coagulation, as fluid floods the lungs. Meanwhile, a host of seemingly unrelated symptoms set in. Blood ...

Medical research

Acute itching in eczema patients linked to environmental allergens

In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines—the standard treatment for itching and allergy—often don't help.

Medical research

New therapeutic approaches for SARS-CoV-2

Medicine has two things to offer when viral pandemics hit: vaccines and therapeutics. While it is hard to undervalue the noble goal of rapidly developing and rolling out safe vaccines that effectively reduce disease severity, ...

Medical research

How the brain paralyzes you while you sleep

We laugh when we see Homer Simpson falling asleep while driving, while in church, and even while operating the Springfield nuclear reactor. In reality though, narcolepsy, cataplexy and rapid eye movement (REM) sleep behavior ...

Medical research

A rift in the retina may help repair the optic nerve

In experiments in mouse tissues and human cells, Johns Hopkins Medicine researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged ...

Medical research

A new strategy for making blood stem cells healthier

The hematopoietic (blood-forming) stem cells (HSCs) residing in our bone marrow produce all of our blood cells, including key immune cells that protect us from bacteria and viruses. As we age, our HSCs become less efficient ...

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Toward new alternatives to animal testing

A novel alternative approach that can identify chemicals which affect male reproductive health without the use of animal tests has been developed in a research project led by the Technical University of Denmark.

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Men more susceptible to COVID-19 than women

Males are more likely to test positive for COVID-19, more likely to have complications and more likely to die from the virus than females, independent of age, according to a new study published this week in the open-access ...

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Temperature scanners of limited value in detecting COVID-19

Making people stand in front of a scanner to have their body temperature read can result in a large number of false negatives, allowing people with COVID-19 to pass through airports and hospitals undetected.

Medical research

Scientists reverse deadly impacts of asthma in mice

Mucus in the lungs can be fatal for asthma patients, but scientists at the University of Colorado Anschutz Medical Campus have broken up those secretions at the molecular level and reversed their often deadly impacts.

Medical research

Weaker skin barrier leads to faster uptake of chemicals

The ability of skin to protect from chemicals is heritable. Some people are less well-protected, which could imply an increased risk of being afflicted by skin disease or cancer. A new study from Karolinska Institutet in ...

Medical research

Promising new antibodies against SARS-CoV-2 found

An international team led by the University of Bonn (Germany) identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are smaller than classic antibodies penetrating the ...

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Protecting lungs from ventilator-induced injury

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

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Study reveals new link to arthritis

A new study by investigators at the Shriners Hospital for Children—St. Louis suggests the damaging effects of obesity are not due to body weight but rather come from something much smaller—biochemical signals released ...

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New findings help explain how COVID-19 overpowers the immune system

Seeking to understand why COVID-19 is able to suppress the body's immune response, new research from the USC Leonard Davis School of Gerontology suggests that mitochondria are one of the first lines of defense against COVID-19 ...

Medical research

Study links severe COVID-19 disease to short telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) in collaboration with the COVID-IFEMA Field Hospital, ...

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Trained medical staff can perform safe, effective hernia surgery

Many sub-Saharan countries have a desperate shortage of surgeons, and to ensure that as many patients as possible can be treated, some operations are carried out by medical professionals who are not specialists in surgery.

Medical research

Scientists develop new gene therapy strategy to delay aging

Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...

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Immune cells discovered in the lungs improve virus defense

A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection ...