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Medical research news
Medical research
Q&A: Two decades of research lead to treatment for rare, painful skin condition
Patients with severe dystrophic epidermolysis bullosa, or EB, have skin so fragile, the slightest touch can lead to blistering and, eventually, large, open wounds that never heal, causing immense pain.
May 3, 2025
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Medical research
Two-week radiotherapy proven as safe and effective as eight-week course for prostate cancer: 10-year follow-up
Prostate cancer is the most commonly diagnosed cancer in men worldwide, accounting for more than 1.4 million new cases each year. For many patients, radiotherapy is a standard treatment option that offers outcomes comparable ...
May 2, 2025
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COVID-19 research overlooks key perspectives from marginalized communities, study finds
During the pandemic, the Centers for Disease Control and Prevention (CDC) reported that people from historically marginalized racial and ethnic groups were more likely than non-Hispanic white people to be infected, be hospitalized ...
May 2, 2025
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US government to require placebo testing of all new vaccines: How will it affect updated COVID shots?
The U.S. Health and Human Services Department says it will require placebo testing of "all new vaccines," raising questions about the rollout of updated COVID-19 vaccines and other vaccines.
May 2, 2025
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Lysosome destabilization found to drive iron-dependent cell death in cancer
The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell death, is also necessary ...
May 1, 2025
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The 'entourage effect'—what we don't know about how cannabis works
In the years since legalization, there has been a tremendous surge in the number of cannabis products available to Canadian consumers, many offering tailored experiences to enhance seemingly any mood or activity.
May 1, 2025
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Environmental health journal suspends submissions amid budget cuts
A well-known U.S. science journal focused on environmental health has stopped accepting new studies, raising alarms among researchers who rely on it heavily.
May 1, 2025
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Rare cancer synovial sarcoma reduced using plasma-activated medium
Plasma-activated medium (PAM) shows tumor-fighting effects against the rare form of cancer known as synovial sarcoma, an Osaka Metropolitan University-led research team has found.
May 1, 2025
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From COVID to cancer: Why Canada's RNA vaccine leadership matters more than ever
As the world marks World Immunization Week, attention turns once again to the lifesaving power of vaccines.
May 1, 2025
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Enzyme-resistant glycan glue ameliorates spinal disk degeneration in animal models
As the world's population ages, intervertebral disk degeneration (IDD) has become a major medical issue, causing chronic lower back pain and mobility issues that diminish the quality of life for millions. The study from the ...
Apr 30, 2025
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Novel rat model could advance COPD-associated cor pulmonale research
Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive pulmonary disease (COPD)-associated cor pulmonale. This model ...
Apr 30, 2025
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Egg white hydrolysates show promise as natural antihypertensive agents
Hypertension is a major public health concern, affecting millions worldwide and increasing the risk of heart disease, stroke, and kidney failure. It is typically characterized by persistent high blood pressure, which can ...
Apr 30, 2025
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Q&A: How halt in funding hurts efforts to ensure safety of patients in medical research
The Trump administration's freeze of more than $2 billion in federal research grants to Harvard has disrupted work in a number of areas, including efforts to ensure the rights and safety of patients who take part in medical ...
Apr 29, 2025
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Study using simulations highlights power of pooled data in environmental health research
Conflicting findings in environmental epidemiology have long stalled consensus on the health effects of toxic chemicals. A new study by Columbia University Mailman School of Public Health published in the American Journal ...
Apr 28, 2025
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Traffic-related ultrafine particles found to influence gene regulation in olfactory cells
Exposure to air pollution–derived ultrafine particles alters gene transcription by epigenetic mechanisms, a new study shows. The changes affected, for example, cellular survival.
Apr 28, 2025
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Covalent Werner helicase inhibitor shows clinical proof-of-concept in Phase I trial
For patients with cancers harboring certain genetic defects, the first-in-class targeted therapy RO7589831, which targets the DNA repair enzyme Werner helicase, demonstrated early signals of efficacy and was generally well-tolerated, ...
Apr 28, 2025
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Computational analysis links blood RNA patterns to ALS diagnosis and prognosis
Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don't know what causes it. To lay the groundwork for ...
Apr 26, 2025
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Experts set research priorities for burn treatment in a project spanning 88 countries
Each year, more than 11 million people worldwide suffer serious life-changing burns, affecting both adults and children. The largest-ever project of its kind—the Priorities in Global Burns Research partnership, led by the ...
Apr 24, 2025
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New method improves survival analysis power in clinical and epidemiological studies
The restricted mean survival time (RMST) analysis technique was introduced in health care research about 25 years ago and since then has become widely used in economics, engineering, business and other professions.
Apr 24, 2025
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Global review identifies best treatments for neuropathic pain
A major international study has provided the most comprehensive evidence to date on treatments for neuropathic pain—defined as pain caused by disease of the nervous system, affecting up to 10% of the population worldwide.
Apr 23, 2025
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Newly discovered cells in connective tissue open up strategy against pancreatic cancer
Researchers at Umeå University, Sweden, have discovered a previously unknown type of connective tissue cells that surround cancer cells in pancreatic tumors. The newly discovered cells counteract tumor development and may ...
Apr 23, 2025
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Drug uptake discovery could allow IV medications to be taken orally
A team of scientists has uncovered the mechanism of cellular uptake for large and polar drugs and devised a novel strategy to optimize the capacity of drug-delivery into these cells. The team was led by Hong-yu Li, Ph.D., ...
Apr 22, 2025
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Blocking APOC1 protein can slow lymphoma cell growth
Diffuse large B-cell lymphoma (DLBCL) is the most common and fast-growing type of non-Hodgkin lymphoma, a cancer that affects the lymphatic system. It makes up around 30–40% of adult non-Hodgkin lymphoma cases worldwide. ...
Apr 22, 2025
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Building 'cellular bridges' for spinal cord repair after injury
Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests.
Apr 21, 2025
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Two brain proteins are key to preventing seizures, research in fruit flies suggests
One in 10 people will have at least one seizure in their life, but effective treatments for seizures remain very limited, in part due to incomplete understanding of the brain mechanisms involved. Now, research in fruit flies ...
Apr 21, 2025
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