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World-first international guidelines weeds-out potentially critical scientific fraud

The number of retractions issued for scientific research articles in 2023 exceeded 10,000—smashing annual records. To date, publishers have struggled to clean up a slew of papers with serious integrity concerns.

Medical research

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

A treatment for metastatic cancer—researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the University of Innsbruck, the Massachusetts Institute of Technology (MIT) and Universität Würzburg have now ...

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Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

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Are patient partners a necessity in research?

The European Alliance of Associations for Rheumatology has long recognized the pivotal role of patients in the development of recommendations, and the role of patients in research is also evolving. But collaboration with ...

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Heart regeneration: Researchers discover key role of growth factor

An international research team, coordinated by academics from the University of Bologna and the IRCCS—Policlinico Sant'Orsola Hospital, has identified a key growth factor capable of exerting a proliferative and regenerative ...

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New insights on polymicrobial infections in chronic lung diseases

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display ...

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Precision medicine for sepsis in children within reach

Sepsis—the leading cause of mortality in children around the world—can present with a wide range of signs and symptoms, making a one-size-fits-all treatment strategy ineffective. Pursuing a precision medicine approach ...

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Blocking key protein normalizes uterine muscle tone, study shows

Abnormal uterine blood flow is a hallmark of hypertensive disorders of pregnancy, including chronic hypertension, preeclampsia and gestational hypertension. Abnormal uterine blood flow is also associated with a low fertility ...