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New role for blood-brain barrier in neuron function and damage

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...

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New study shows Rhodiola rosea root might be beneficial for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise ...

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Sugar chains on cell surfaces direct cancer cells to die

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...

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Monkeypox virus found in anal samples from asymptomatic MSM

A brief research report documents positive monkeypox virus PCR results found in anal samples taken from asymptomatic MSM (men who have sex with men). These findings suggest that vaccination limited to those with known exposure ...

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Why thinking hard makes you tired

It's no surprise that hard physical labor wears you out, but what about hard mental labor? Sitting around thinking hard for hours makes one feel worn out, too. Now, researchers have new evidence to explain why this is, and, ...

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Issues with fracture healing in people with Down syndrome

New research from the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) is the first to provide direct experimental evidence that people with Down syndrome may not heal from bone fractures.

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Scientists identify pathway to curb spread of brain cancer

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, ...

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Collagen a key player in breast cancer metastasis

Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate Professor Thomas Cox, Head of ...

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New target identified for treatment of premature aging disease

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered. ...

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ALS: Early disease mechanisms discovered

Currently, there is no cure for amyotrophic lateral sclerosis (ALS). Things could soon change, however. Researchers at FAU and the University of California San Diego (UCSD) have identified a protein that already displays ...

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Survey looks at why patients request stem cell treatments

In one of the first studies of its kind, Mayo Clinic researchers have analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The ...

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Health research: Giving greater consideration to gender diversity

Gender diversity is still understudied in health research. This is shown by a recent survey conducted by researchers at the Institute for Public Health and Nursing Research at the University of Bremen. A distinction into ...

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Diabetes: A step closer to a life without insulin

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive. ...

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Study reveals new mode of triggering immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers ...

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Loss of male sex chromosome leads to earlier death for men

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows. The finding may help explain ...

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A new treatment approach for cystic fibrosis

Antisense oligonucleotides, or ASOs, are molecules that can be used to control protein levels in cells. Cold Spring Harbor Laboratory Professor Adrian Krainer leveraged ASO technology to develop the first FDA-approved treatment ...

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Study suggests that C. difficile drives some colorectal cancers

Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing ...

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Brass, woodwind instruments emit respiratory particles, study finds

Just like coughing, sneezing, talking and singing, playing wind instruments—particularly those in the brass section—can spread respiratory particles that may carry the COVID-19 virus, according to a Colorado State University ...

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Women with stroke disadvantaged in critical treatment time window

Despite women with stroke being more likely than men to arrive at the hospital by ambulance, their care is less likely to follow a smooth pathway of care along the way, according to new research published in the Medical Journal ...

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How gut microbes can evolve and become dangerous

Gut microbes have been linked to both good health and the promotion of diseases such as autoimmune disorders, inflammatory bowel diseases, metabolic syndrome, and even neuropsychiatric disorders.

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Microparticles could be used to deliver 'self-boosting' vaccines

Most vaccines, from measles to COVID-19, require a series of multiple shots before the recipient is considered fully vaccinated. To make that easier to achieve, MIT researchers have developed microparticles that can be tuned ...