Oncology & Cancer

DDX41 and its unique contribution to myeloid leukemogenesis

In an editorial paper published in Oncotarget titled, "DDX41 and its unique contribution to myeloid leukemogenesis," researcher Hirotaka Matsui from the National Cancer Center Hospital in Tokyo, Japan, and Kumamoto University ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.

In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]

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