Oncology & Cancer

Milestone reached in new leukemia drug

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute (DFCI), have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

Medical research

New cancer treatment not as toxic as others

A QIMR Berghofer study has identified how a newly approved blood cancer drug works and found the treatment is better than other drugs at targeting cancer stem cells while causing minimal damage to healthy cells.

Oncology & Cancer

Common TB vaccine associated with lower lung cancer rates

(HealthDay)—Childhood vaccination with the bacille Calmette-Guérin (BCG) vaccine is associated with a reduced risk for lung cancer, according to a study published online Sept. 25 in JAMA Network Open.

Medications

Metabolic syndrome: New use for an old drug

New drugs can be developed from old ones. This revolutionary pharmacological approach was confirmed by a study published today in Nature Communications that was conducted by two major research centers of the University of ...

Medications

Cocktail proves toxic to leukemia cells

A combination of drugs that affect mitochondria—the power plants inside cells—may become the best weapons yet to fight acute myeloid leukemia, according to Rice University researchers.

Oncology & Cancer

Pediatric cancers: Why some forms of leukemia only affect children

Acute myeloid leukemia (AML) mainly affects children, with often poor prognosis despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children ...

Oncology & Cancer

Learning to stop cancer at its roots

Why do some cancers come back? Sometimes, a treatment can effectively eliminate cancer cells to undetectable levels, but, if the treatment stops, cancer may return. This is the case of chronic myeloid leukemia treated with ...

Oncology & Cancer

Treating the TOTAL patient: clinical trial reduces relapse

Despite modern therapies, 10% of patients with acute lymphoblastic leukemia (ALL) treated in the U.S. relapse, which dramatically reduces their chance of survival. Results from a St. Jude Children's Research Hospital clinical ...

Oncology & Cancer

Gilteritinib superior in relapsed, refractory FLT3-mutated AML

(HealthDay)—For relapsed or refractory acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase 3 gene (FLT3), treatment with a selective FLT3 inhibitor, gilteritinib, results in significantly longer ...

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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.

In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]

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