Medications

Antibody eradicates leukemia stem cells

The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80 percent of people with CML who received the drug, the disease went into complete ...

Oncology & Cancer

Effects on quality of life mixed for therapy of multiple myeloma

(HealthDay)—Most dimensions of quality of life (QoL) are impaired in patients with relapsed/refractory multiple myeloma, and treatment may have mixed effects on QoL, according to a study published online Sept. 26 in Leukemia ...

Immunology

A new regulator of B cell development

Interleukin-33 (IL-33) drives inflammatory responses in allergic and nonallergic disease. Epithelial cells in the lungs, gastrointestinal tract and elsewhere release IL-33, which activates the ST2 receptor on immune cell ...

Oncology & Cancer

Leukemia drug shows promise for treating a childhood brain cancer

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...

Genetics

Exploring the risk of ALL in children with Down syndrome

Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome. Historically, children with ...

Oncology & Cancer

Blast count prognostic for CML presenting in advanced phase

(HealthDay)—Blast count seems to be the main prognostic count for patients with chronic myeloid leukemia (CML) presenting in an advanced phase, according to a study published online Aug. 27 in the American Journal of Hematology.

Oncology & Cancer

Many older patients with AML not receiving active treatment

(HealthDay)—Many older patients with acute myeloid leukemia (AML) do not receive any active treatment, and they have worse survival than those receiving active treatment, according to a study published online Sept. 4 in ...

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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.

In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]

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