Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet ...
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Americans die of heart or cardiovascular disease at an alarming rate. In fact, heart attacks, strokes and related diseases will kill an estimated 610,000 Americans this year alone. Some medications help, but to better tackle ...
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Until recently, scientific research concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent - a vast universe of non-coding genetic material previously ...
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Gene editing of bone marrow stem cells in pigtail macaques infected with simian/human immunodeficiency virus (SHIV) significantly reduces the size of dormant "viral reservoirs" that pose a risk of reactivation. Christopher ...
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A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression. This mechanism includes potential targets for next-generation drug discovery ...
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Via drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A steroid hormone, dehydroepiandrosterone ...
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Hematopoietic stem cells (HSCs) are a class of stem cells located in bone marrow. HSCs give rise to every type of blood cell—from the red blood cells that carry oxygen to the white blood cells of the immune system. Bone ...
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Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural ...
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An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.
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For years, scientists have observed that when male and female mice eat the same high-fat diet, the males gain significantly more weight than the females. The reasons for this difference between sexes are not completely understood, ...
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