Common degenerative brain disease may begin to develop already in middle age
Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study by the University of Helsinki and the University of Tampere. In the study, almost 1 in 10 of over-50-year-olds ...
Mar 26, 2024
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Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear
The survival of neurons, unlike most other cells in the body, depends largely on the energy provided by mitochondria, intracellular organelles that contain their DNA to function properly.
Mar 25, 2024
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Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS
Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and muscle control is progressively lost, leading to a fatal outcome. The causes of ALS are currently unknown, ...
Mar 22, 2024
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Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows
On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, ...
Mar 22, 2024
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Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases
In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, ...
Mar 20, 2024
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New study reveals how the brain orchestrates motions in partnership with sensory cues from the body
Motor neurons are the cells the brain uses to command muscles to act. Scientists typically thought of them as simple connections, much like the cables that link computers with their accessories. Now, in fly studies, researchers ...
Mar 20, 2024
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Biologists discover propionate supplementation as a potential treatment for Parkinson's disease
A research team led by Professor Chaogu Zheng from the School of Biological Sciences at The University of Hong Kong (HKU) recently discovered that propionate, a short-chain fatty acid (SCFA), strongly suppressed neurodegeneration ...
Mar 19, 2024
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Alzheimer's and Parkinson's biomarkers show promise for early diagnosis
New research supported by the Knight Initiative for Brain Resilience at Stanford's Wu Tsai Neurosciences Institute highlights significant strides researchers have made in developing biomarkers for the early detection and ...
Mar 19, 2024
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New technique for Parkinson's stem cell brain repair brings promise for patients
Neuroscientists at the University of Galway have made an exciting discovery that could revolutionize stem cell-based brain repair therapy for Parkinson's disease.
Mar 19, 2024
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Team develops fluid biomarker for early detection of amyotrophic lateral sclerosis and frontotemporal dementia
Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk ...
Mar 18, 2024
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Clinical trial shows subcutaneous infusion pump safe, effective for Parkinson's treatment
An international, multisite Phase III trial, co-led by a University of Cincinnati researcher, has found that a Parkinson's disease medication delivered through an infusion pump is safe and effective at reducing symptoms ...
Mar 18, 2024
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First-of-its-kind super minigene to boost spinal muscular atrophy research
Ravindra Singh has spent years studying a gene that, when missing or mutated, causes spinal muscular atrophy (SMA), a deadly disease that's among the most common genetic disorders in children. His team's latest work will ...
Mar 13, 2024
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How invisible presences hijack the social counting brain in Parkinson's disease
If you had to estimate the number of people in a room, without counting them one by one, by nature you would overcount them. That's because—simply put from a Darwinian perspective of how we have evolved—it's better to ...
Mar 12, 2024
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Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease
A mutated protein expressed in lysosomes may contribute to Parkinson's disease, according to a new Northwestern Medicine study published in the Journal of Cell Biology.
Mar 12, 2024
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Scientists uphold claim that intermittent fasting and Ramadan may lower risk of Alzheimer's and Parkinson's
People who fast intermittently and observe Ramadan, the Muslim month of fasting, may lower the risk of age-related neurodegenerative diseases such as Alzheimer and Parkinson's, according to a study published in the journal ...
Mar 5, 2024
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Patients with Parkinson's disease who experience freezing of gait have sleep disorders, study shows
Parkinson's disease patients who experience freezing of gait (a sudden inability to initiate or continue movement, often resulting in a fall) wake up several times during the night, feel sleepy during the day, and have REM ...
Mar 5, 2024
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Study shows differences in how patients with impulse control disorder process consequences
Parkinson's disease is a neurological disorder that affects movement and muscle control. One characteristic of the disease is the deficiency of dopamine, a neurotransmitter or brain chemical that plays a role in movement ...
Mar 4, 2024
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New animal model created to study Parkinson's disease before neurodegeneration appears
A research team led by the Institut de Neurociències at the UAB has managed to generate and validate a new animal model. This model enables the examination of the initial phases of Parkinson's disease, occurring prior to ...
Mar 4, 2024
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