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Medical research

A blood test for your body clock? It's on the horizon

What time is your body clock set on?

Obstetrics & gynaecology

Nearly half of surveyed female surgeons experience major pregnancy complications

While only one in five practicing surgeons in the U.S. is female, women are entering the surgical field in increasing numbers. Women comprised 38 percent of surgical residents in 2018, but they nonetheless continue to face ...

Diseases, Conditions, Syndromes

To stop a pandemic in its tracks, coordinate across borders

On March 16, 2020, the governors of New York, New Jersey, and Connecticut announced "a regional approach to combatting COVID-19," citing an absence of federal leadership and national standards. Pennsylvania joined two days ...

Medical research

Researchers develop 'dimmer switch' to help control gene therapy

In a major advancement in the field of gene therapy for rare and devastating diseases, researchers at Children's Hospital of Philadelphia (CHOP) have developed a "dimmer switch" system that can control levels of proteins ...

Oncology & Cancer

Refining treatment for childhood leukemia

Scientists at St. Jude Children's Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial ...

Psychology & Psychiatry

New model helps map the individual variations of mental illness

The diagnosis of mental illnesses such as major depression, schizophrenia, or anxiety disorder is typically based on coarse groupings of symptoms. These symptoms, however, vary widely among individuals as do the brain circuits ...

Alzheimer's disease & dementia

Buying time for people approaching Alzheimer's

Australians living with mild cognitive impairment (MCI) could know five years in advance whether they are at high risk of developing Alzheimer's disease—the most common form of dementia—according to new research from ...

Diseases, Conditions, Syndromes

New treatment pathways for hepatitis C

A newly published Burnet Institute study has demonstrated the feasibility and effectiveness of simplified clinical pathways for treatment of hepatitis C (HCV) in Myanmar.

Psychology & Psychiatry

Helping new moms sleep better without medication

Poor sleep during pregnancy and in the first months post-birth can have long lasting psychological and physical consequences for both mother and baby. New research from Monash University has found that a non-drug sleep program, ...

Medical research

Synthetic tissue model with blood vessels developed

Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain ...

Oncology & Cancer

Tiny bubbles used to treat common childhood cancer

Researchers at UCL have developed a new way to deliver drugs that can shut down cancer-promoting mutations in neuroblastoma. The findings in mice, show the method, which uses tiny bubbles to deliver therapies directly to ...

Psychology & Psychiatry

Discovery points to ketamine's long-term antidepressant effects

Building on recent research confirming how ketamine induces rapid antidepressant action, Professor of Pharmacology Lisa Monteggia and her collaborators show how the molecular mechanism of the gene MeCP2 and associated synaptic ...

Neuroscience

Motivation depends on how the brain processes fatigue

How do we decide whether or not an activity which requires work is 'worth the effort'? Researchers at the University of Birmingham & University of Oxford have shown that the willingness to work is not static, and depends ...

Immunology

A molecular traffic light for infectious disease testing

Home test kits to check for COVID-19 spike proteins and anti-COVID-19 antibodies are fast and simple to use but lack the sensitivity and accuracy of laboratory tests. Researchers from Eindhoven University of Technology with ...

Genetics

Three genes determine heart cell growth

Heart disease has long been the leading cause of death globally. One reason is that the heart has poor regenerative properties, causing damage to accumulate. Scientists have speculated that understanding how the heart grows ...

Psychology & Psychiatry

Another byproduct of the pandemic: paranoia

The COVID-19 pandemic increased our feelings of paranoia, particularly in states where wearing masks was mandated, a new Yale study has shown. That heightened paranoia was particularly acute in states where adherence to mask ...

Alzheimer's disease & dementia

'Light flash' treatment might help slow Alzheimer's

While efforts to develop Alzheimer's medications have so far borne little fruit, new research highlights the therapeutic promise of two non-drug tools: light and sound.