Researchers at Vanderbilt University identified a molecular approach to extend the antidepressant effects of ketamine in mice by applying BCI, a compound that inhibits DUSP6 to sustain ERK pathway activation. Findings suggest ...
Many patients suffer not only from respiratory symptoms due to their COVID-19 disease, but also from significantly reduced physical performance. A patent-protected tablet (CICR-NAM) developed at the University Hospital Schleswig-Holstein ...
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At the level of molecules and cells, ketamine and dexmedetomidine work very differently, but in the operating room they do the same exact thing: anesthetize the patient. By demonstrating how these distinct drugs achieve the ...
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About 15% of patients with typhoid fever develop serious neurological complications, including delirium and seizures, that are collectively described as acute encephalopathy. Until now, however, scientists have not clearly ...
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High-risk neuroblastoma kills roughly half of affected children because the tumor can switch cell identity and evade therapy. By combining single-cell multi-omics with spatial transcriptomics, researchers at Karolinska Institutet ...
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New research being presented at the European Congress on Obesity (ECO25) in Malaga, Spain (11–14 May) and published in the journal eClinicalMedicine finds that first-generation weight-loss medications like liraglutide and ...
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The UK is facing what charities are calling an eating disorder epidemic, with an estimated 1.25 million people affected. These conditions have the highest mortality rate of any mental health illness, making early intervention ...
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Epilepsy, one of the most common neurological disorders characterized by recurrent seizures, affects over 70 million people worldwide. In the United States, about 3.4 million people live with this challenging condition. Around ...
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While health status is an important factor in whether a person is able to grow old in their home and community (age in place), researchers at McGill University have shed new light on the social factors that can also have ...
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A daily pill to treat endometriosis has just been recommended by the National Institute for Health and Care Excellence (Nice). Once available on the NHS, linzagolix will provide a new treatment option for those who have been ...
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