Alzheimer's disease & dementia

A potential new treatment target for Alzheimer's disease

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

Gastroenterology

Persistence pays off in the human gut microbiome

The human gut microbiome is a complex community of trillions of microbes that are constantly interacting with each other and our bodies. It supports our wellbeing, immune system and mental health—but how is it sustained?

Medical research

Harmful protein waste in the muscle

An international team of researchers led by the University of Bonn has identified the cause of a rare, severe muscle disease. According to these findings, a single spontaneously occurring mutation results in the muscle cells ...

Cardiology

Improving dialysis through redesign of arteriovenous grafts

People with end-stage renal disease often undergo hemodialysis, a life-sustaining blood-filtering treatment. To make the process as fast and efficient as possible, many people have "hemodialysis grafts" surgically implanted. ...

Other

Physical activity may curb health care worker burnout

There is no question that the pandemic has been immensely stressful for health care workers, especially for those on the frontline of patient care. Yet, even before the pandemic, the regular demands of many health care industry ...

Psychology & Psychiatry

Inflammatory process alteration accompanies opioid use disorder

Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths—nearly 50,000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical ...

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