Oncology & Cancer

Autophagy genes act as tumor suppressors in ovarian cancer

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy ...

Genetics

New gene mutation associated with Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study. The variant plays a role in lipid metabolism. According to the researchers, patients carrying the mutation ...

Oncology & Cancer

'Genetic rewiring' drives cancer's drug resistance

A tiny molecule of RNA—known as 'micro RNA' - plays a key role in 'rewiring' cancer cells so they can resist the effects of chemotherapy, a new study reveals.

Genetics

CRISPR 'minigene' approach stops genetic liver disease in mice

A new CRISPR gene-editing technique prevented a genetic liver disease known to be driven by hundreds of different mutations and improved clinical symptoms in mice, Penn Medicine researchers reported in new proof-of-concept ...

page 1 from 2