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Genetics news

Oncology & Cancer

Cancer-predisposition variants associated with adverse outcomes in rhabdomyosarcoma

Germline cancer-predisposition variants (CPVs) can be helpful in predicting risk in some pediatric cancers. However, CPV risk association in children with rhabdomyosarcoma has not been well studied. A new report led by researchers ...

Oncology & Cancer

Discovery suggests new strategy against follicular lymphoma

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some ...

Genetics

Longevity scores show signs of resilience to certain diseases

Using data from four studies that connect genetic variants to lifespan, scientists have developed 11 different polygenic longevity scores (PLS) that predict both long life and resilience to some age-related conditions such ...

Genetics

Music and genomes: Beethoven's genes put to the test

To what extent are exceptional human achievements influenced by genetic factors? This question, dating back to the early days of human genetics, seems to be easier to address today as modern molecular methods make it possible ...

Genetics

Colorectal cancer gene implicated in broad range of solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel ...

Genetics

The genomic architecture of inherited DNA variants

You have your mother's eyes and your father's smile, but genetics is much more than just what's on the surface. In a study that spans more than a decade, researchers at Baylor College of Medicine have looked at generations ...

Genetics

Immune cells identified as key players in brain health

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding ...