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Genetics news
Genetics
Genetic analysis of all-women extreme divers finds changes linked to blood pressure and cold tolerance
A new analysis of a group of all-women extreme divers off the coast of Korea has uncovered genetic differences that could help them survive the intense physiological stresses of free-diving—and could ultimately lead to ...
May 2, 2025
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Genetics
Distinct placental gene expression in males and females could shed light on pregnancy outcomes
The genes of male and female placentas have marked differences in how they are expressed, according to a study by researchers at the National Institutes of Health (NIH) and other institutions. These differences involve the ...
May 2, 2025
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Origins of common lung cancer that affects smokers discovered
The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the ...
May 1, 2025
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AI uncovers hidden patterns in genes that shape disease vulnerability
Artificial intelligence (AI)-powered protein models combined with genome sequencing technology could help scientists better diagnose and treat genetic diseases, according to new research from The Australian National University ...
May 1, 2025
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Enzyme PRMT5 found to drive chemotherapy resistance in ovarian cancer
Northwestern Medicine scientists have identified a key driver of chemotherapy resistance in advanced ovarian cancer, according to a study published in the Journal of Clinical Investigation.
May 1, 2025
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Investigational gene therapy gives children with rare immune disorder a new lease on life
An investigational gene therapy has successfully restored immune function in all nine children treated with the rare and life-threatening immune disorder called severe leukocyte adhesion deficiency-I, or LAD-I, in an international ...
Apr 30, 2025
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Crowdsourcing the brain: Meta-atlas reveals new clues about development and disease
One in three Americans is likely to be affected by a brain disorder in their lifetime. Many of these conditions, such as Alzheimer's disease or severe developmental disorders, have no reliable treatment.
Apr 30, 2025
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A protein link between brain diseases and leaky blood vessels
Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain's ...
Apr 30, 2025
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Single-cell atlas reveals hidden patterns of differentiation in acute myeloid leukemia
Princess Margaret Cancer Center at University Health Network-led researchers constructed a detailed single-cell atlas of human blood development, improving understanding of leukemia formation and enabling a more precise classification ...
Seasonal gene expression affects drug effectiveness and metabolism in primates, study shows
Nagoya University researchers in Japan have found that drug effectiveness, alcohol tolerance, and carbohydrate metabolism change with the seasons. Their findings are based on a comprehensive seasonal gene expression map, ...
Apr 30, 2025
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Researchers discover novel gene variant in Finns that increases risk of Alzheimer's disease
Found in the Finnish population, a rare variant of the TYROBP gene significantly increases the risk of Alzheimer's disease, a new study led by the University of Eastern Finland shows. This gene variant affects the function ...
Apr 30, 2025
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Single DNA mutation disrupts key tumor-suppressing pathways, elevating blood cancer risk
Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.
Apr 30, 2025
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PBAF chromatin may explain melanoma spread to the brain
Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in Molecular Cell, highlights ...
Apr 30, 2025
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Genetic factors highlight the many ways health and height are linked
Height is determined by thousands of signals in our genes. Three world experts on human growth, including Associate Professor Louise Bicknell from Otago's Department of Biochemistry, have undertaken a significant review summarizing ...
Apr 30, 2025
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Clusterin expression marks aging in hematopoietic stem cells
In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging. ...
Apr 30, 2025
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FDA approves Zevaskyn for rare, genetic skin disorder
The U.S. Food and Drug Administration has approved Abeona Therapeutics' Zevaskyn (prademagene zamikeracel) for patients with the rare, genetic skin disorder recessive dystrophic epidermolysis bullosa.
Apr 30, 2025
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Platform technology screens millions of drugs and genes to reveal new therapeutic pathways
Researchers from the University of Adelaide have developed a new technology for drug and functional genomics screenings, which could reshape the way diseases are treated.
Apr 29, 2025
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Cancer-linked proteins have different functions in neurodevelopmental disorders, study finds
Some proteins in human cells that are implicated in cancer also have causal roles in neurodevelopmental disorders, raising the possibility of repurposing targeted cancer therapies to help address neurodevelopmental diseases.
Apr 29, 2025
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Scientists discover how circular RNA affects wound healing
Researchers at Karolinska Institutet have identified a new mechanism where circular RNA plays a crucial role in wound healing, which could lead to new therapies to improve wound healing and reduce scarring. The study is published ...
Apr 29, 2025
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Computational analysis clarifies cancer risk for families with genetic variants
QIMR Berghofer-led research has shown that new advanced computational prediction tools can improve the accuracy of genetic testing for families affected by an inherited condition that significantly increases their risk of ...
Apr 29, 2025
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How human genetics and intratumoral microbiota affect colorectal cancer
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance ...
Apr 29, 2025
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Pregnancy-related proteins in tumors linked to worse survival in female lung cancer patients
Lung cancer can co-opt genes that normally help a fetus develop and evade the mother's immune system. And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men and women, female ...
Apr 29, 2025
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Compact gene circuit uses microRNA to fine-tune therapy for rare diseases
Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of the missing genes to ...
Apr 28, 2025
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A new computational framework illuminates the hidden ecology of diseased tissues
To understand what drives disease progression in tissues, scientists need more than just a snapshot of cells in isolation—they need to see where the cells are, how they interact, and how that spatial organization shifts ...
Apr 28, 2025
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Long-term survival rates of some acute myeloid leukemia patients could double with sensitive bone marrow test
A highly sensitive bone marrow test could double survival rates for some groups of younger adults with acute myeloid leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.
Apr 28, 2025
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