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Genetics news

Genetics

'Abnormal' protein could be common link between all forms of motor neuron disease

Researchers have found an abnormal protein usually linked to a rare inherited form of motor neuron disease is present in all types of motor neuron disease, suggesting a common link between the different forms of the disease.

Genetics

Study uncovers what happens inside artery plaque to trigger strokes

Heart attacks and strokes are a leading cause of death in the United States, but scientists are still working to understand one of their primary triggers. What causes plaque buildup within arteries to become unstable, leading ...

Oncology & Cancer

Genetic mapping of tumors reveals how cancers grow

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically over time. This has been made possible using a new ...

Genetics

New antibiotic resistance genes identified in tuberculosis

A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. ...

Oncology & Cancer

A better roadmap for beating deadly leukemia

Acute myeloid leukemia, or AML, is the most common acute blood cancer in adults—and one of the most difficult to treat. Scientists at Oregon Health & Science University have discovered a potential new target for stopping ...

Oncology & Cancer

How common genetic alterations cause kidney cancer

An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.

Genetics

Researchers refine understanding of fetal hemoglobin regulation

Researchers at Children's Hospital of Philadelphia (CHOP) have discovered a new part of the regulatory cascade responsible for silencing fetal hemoglobin in adult cells. The findings, published today in Nature Genetics, refine ...

Genetics

Brain mechanism underlying evolution of anxiety

Monoamine neurotransmitters such as serotonin and dopamine play important roles in our cognitive and emotional functions. Their evolutionary origins date back to metazoans, and while the function of related genes is strongly ...

Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

Oncology & Cancer

9 common questions about genetic testing for cancer

Your genes play a role in nearly all areas of your health. A gene is like an instruction manual for your body that tells your body how to function, develop and stay healthy. People have about 20,000 genes in their bodies.

Genetics

Human lung proteins can advance or thwart SARS-CoV-2 infections

Researchers have taken an important step toward understanding the microscopic battle that plays out between our lung cells and the SARS-CoV-2 virus that causes COVID-19. A UC Berkeley-led study has identified specific proteins ...

Genetics

CRISPR therapeutics can damage the genome

Researchers at Tel Aviv University warn that CRISPR therapeutics can damage the genome. They caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover ...

Genetics

Gene variant links trigger finger and carpal tunnel syndrome

A new NDORMS study, published in The Lancet Rheumatology, has found a genetic variant that increases the risk of both carpal tunnel syndrome and trigger finger, and opens the door for new therapies that involve blocking the ...

Oncology & Cancer

Hallmark cancer gene regulates RNA 'dark matter'

A key genetic mutation that occurs early on in cancer alters RNA "dark matter" and causes the release of previously unknown RNA biomarkers for cancer early detection, a new study by UC Santa Cruz researchers published in ...