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Genetics news
Medical research
Researchers develop 'dimmer switch' to help control gene therapy
In a major advancement in the field of gene therapy for rare and devastating diseases, researchers at Children's Hospital of Philadelphia (CHOP) have developed a "dimmer switch" system that can control levels of proteins ...
8 hours ago
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Genetics
Gene associated with autism linked to itch response
A pilot study from North Carolina State University has found that a gene associated with autism spectrum disorder (ASD) and pain hypersensitivity may actually decrease itch response. Atopic dermatitis and pain hypersensitivity ...
6 hours ago
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Genetic variant linked to hearing loss in children treated with common chemotherapy drug
A University of Alberta research lab has helped identify a genetic variant that increases the risk of hearing loss in children with cancer who are treated with the widely used drug cisplatin.
16 hours ago
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Three genes determine heart cell growth
Heart disease has long been the leading cause of death globally. One reason is that the heart has poor regenerative properties, causing damage to accumulate. Scientists have speculated that understanding how the heart grows ...
12 hours ago
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Genomic test could help predict aggressive disease in men newly diagnosed with prostate cancer
After a biopsy comes back positive for prostate cancer, patients and their doctors are often left with a choice between taking a watch-and-wait approach, known as active surveillance, or proceeding with surgery or radiation.
Jul 27, 2021
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DNA tags enable blood-based tests to assess cancer treatment outcomes
Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer ...
Jul 27, 2021
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Rare inherited variants in previously unsuspected genes may confer significant risk for autism
Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more ...
Jul 26, 2021
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New statement provides path to include ethnicity, ancestry, race in genomic research
Genomic studies have produced advances in how to calculate and reduce heart-disease risk, however, the benefits don't necessarily apply to people from historically marginalized racial and ethnic groups and Indigenous populations. ...
Jul 26, 2021
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The potential role of 'junk DNA' sequence in aging, cancer
The human body is essentially made up of trillions of living cells. It ages as its cells age, which happens when those cells eventually stop replicating and dividing. Scientists have long known that genes influence how cells ...
Jul 23, 2021
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'Noisy' gene expression plays key role in development and may help improve stem cell therapies
To speed up a chemical reaction, a chemist might place the reactants over a Bunsen burner. Adding heat increases the degree of random movements and collisions of particles, accelerating the reaction.
Jul 23, 2021
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Links between genetic risk, glaucoma prevalence examined
(HealthDay)—Polygenic variants are associated with comparable risk for developing open-angle glaucoma as that associated with the most common single-gene pathogenic variant, according to a study published online July 15 ...
Jul 23, 2021
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Largest-ever type 1 diabetes genetic study identifies potential treatment targets
Scientists have completed the largest and most diverse genetic study of Type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.
Jul 22, 2021
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Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss
A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH's National Eye Institute. The findings suggest a way forward for developing neuroprotective ...
Jul 22, 2021
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Geneticists reveal how mutation causes childhood cancer, then use drug to reverse its effects
Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable childhood cancer known as diffuse midline glioma (DMG), and—in lab studies working with ...
Jul 22, 2021
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Unlocking the genetic clues behind aortic aneurysm
A new study increases knowledge of the genetics behind aortic aneurysm, a disease that can spark life-threatening events like aortic dissections and ruptures.
Jul 22, 2021
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Scientists provide new insight on how to stop transcription of cancer cells
Scientists from the UCLA Jonsson Comprehensive Cancer Center have identified a key protein, transcription factor TAF12, that plays a critical role in the formation of a preinitiation complex, which consists of over one hundred ...
Jul 22, 2021
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Papua New Guineans show signs of biological adaptations to altitude
High altitude environments are one of the most demanding habitats in which humans have ever lived. This difficulty is mainly due to hypoxia: oxygen is less available to human tissues at high altitude. However, several populations ...
Jul 21, 2021
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Researchers discover nucleotide sequence responsible for effectively fighting pathologies
Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors). The discovery will help predict errors in microRNA behavior and create drugs that can detect ...
Jul 21, 2021
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Gene expression mechanism may have immunity, cancer implications
Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...
Jul 20, 2021
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Treatment for rare Bachmann-Bupp syndrome developed in 16 months
Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative ...
Jul 20, 2021
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