Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator designed for tumors with TP53 Y220C, and observed antitumor activity across multiple solid tumor types ...
Neuroscientists at King's College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer's disease. Published in Translational Psychiatry, the study also ...
11 hours ago
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Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to produce viral proteins and thus spread more quickly. This is the main conclusion of a study by Pompeu ...
Mar 7, 2026
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GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health. ...
Mar 6, 2026
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Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are eligible for the procedure. ...
Mar 6, 2026
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Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond adequately to conventional ...
Mar 6, 2026
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When a bacterium becomes resistant to one antibiotic, it may sometimes become more sensitive to another. This biological side-effect offers an unexpected opportunity in the fight against antibiotic resistance.
Mar 6, 2026
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Psilocybin—the psychoactive compound in "magic mushrooms"—is gaining scientific attention for its potential in treating neuropsychiatric conditions including depression, anxiety, substance use disorders and certain neurodegenerative ...
Mar 6, 2026
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A White House briefing in September 2025 that raised concerns about acetaminophen use during pregnancy and promoted the drug leucovorin as a potential autism treatment was followed by sharp changes in how doctors prescribed ...
Mar 6, 2026
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For people who have survived a heart attack, the notion of one shot in the arm to help the heart heal, for weeks after, may seem far-fetched. But thanks to a team of researchers, including a Texas A&M University professor, ...
Mar 5, 2026
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