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Medications

Potential COVID-19 drug is successful in lab study

A new potential therapy for COVID-19 developed by researchers at Rush University Medical Center has shown success in preventing the disease's symptoms in mice.

Medications

New delivery method promises relief from antipsychotic medication's adverse side effects

A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.

Medications

New COVID-19 treatment trial results published

A clinical trial involving COVID-19 patients hospitalized at UT Health San Antonio and University Health, among roughly 100 sites globally, found that a combination of the drugs baricitinib and remdesivir reduced time to ...

Medications

Inhaled treprostinil beneficial in pulmonary hypertension

(HealthDay)—Inhaled treprostinil improves exercise capacity in patients with pulmonary hypertension due to interstitial lung disease, according to a study published online Jan. 13 in the New England Journal of Medicine.

Medications

Simple monitoring could reduce medicine misuse in care homes

New research from Swansea University suggests that a simple nurse- or carer-led medicines' monitoring system can help reduce medication-related illness for people living in residential care homes—and the process takes just ...

Medications

Investigational ALS drug pridopidine enters trial

In 2020, the Sean M. Healey & AMG Center at Massachusetts General Hospital launched the first platform trial for amyotrophic lateral sclerosis (ALS), in which multiple treatments are tested and evaluated simultaneously to ...

Medications

Sitagliptin promising addition for preventing acute GVHD

(HealthDay)—For patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation, sitagliptin combined with tacrolimus and sirolimus results in a low incidence of grade II to IV acute graft-versus-host ...

Medications

Repeated ketamine infusions reduce PTSD symptom severity

Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, ...

Medications

Potential new prescription strategy for stroke discovered

Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that a combination of an LSU Health-patented drug and selected DHA derivatives is more effective in protecting brain cells and increasing ...

Medications

Researcher urges caution using remdesivir to treat COVID-19

While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its ...

Medications

Anticoagulants not tied to higher risk for GI bleed in COVID-19

(HealthDay)—Use of anticoagulation or antiplatelet agents is not a risk factor for gastrointestinal (GI) bleeding among hospitalized COVID-19 patients, according to a study published online Dec. 20 in the Journal of Internal ...

Medications

A first look at how the drug salvinorin A works in the brain

Recent interest in developing therapies from hallucinogenic drugs has scientists exploring how these chemicals work in the brain. Recently, Johns Hopkins Medicine researchers imaged the brains of people who had vaped salvinorin ...

Medications

Anti-diarrhea drug drives cancer cells to cell death

The research group led by Dr. Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could ...

Medications

Buprenorphine prescription fills for OUD plateau during pandemic

(HealthDay)—The number of individuals filling buprenorphine prescriptions for opioid use disorder (OUD) has plateaued but not decreased during the COVID-19 pandemic, according to a research letter published online Dec. ...

Medications

Testosterone nasal spray to treat anxiety disorders

A testosterone-containing nasal spray received its second U.S. patent and its first patent in Europe, making it the first testosterone therapy licensed to treat anxiety disorders.

Medications

Antibody cocktail enhances clearance of SARS-CoV-2 virus

(HealthDay)—An interim analysis of data from an ongoing phase 1 to 3 trial shows that an antibody cocktail enhances clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, according to a study published ...

Medications

Rimegepant bests placebo for preventing migraine

(HealthDay)—Taken every other day, rimegepant demonstrates efficacy for the preventive treatment of migraine, according to a study published online Dec. 15 in The Lancet.