The human immune system has specialized cells called CD4 cytotoxic T lymphocytes (CD4 CTLs), which have been shown to kill tumor cells in some cancers. When a person gets sick, these cells multiply in a process called clonal ...
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As the immune system battles cancer, chronic stimulation gradually drives T cells to a state of exhaustion. But some of these exhausted T cells can lose expression of the exhaustion marker LAG3, move out of the tumor and ...
Aug 18, 2026
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A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that inflammatory arthritis occurring as a side effect of immune checkpoint inhibitors behaves like an immune-memory disease, suggesting ...
Aug 12, 2026
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Northwestern Medicine scientists have uncovered a previously hidden immune environment in the thymus that may help drive myasthenia gravis (MG), a chronic autoimmune disease that causes muscle weakness and fatigue, mainly ...
Aug 17, 2026
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For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize ...
Aug 12, 2026
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Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's ...
Aug 13, 2026
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Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA ...
Aug 15, 2026
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Outfitting cells in "invisibility cloaks" may offer an easier, less damaging treatment pathway for people with diabetes undergoing cell therapy, according to researchers at Penn State.
Aug 14, 2026
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We usually think of bodily sensations as information the brain receives. What if the way we attend to those sensations can feed back and change the biological response itself?
Aug 17, 2026
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For more than a decade, CAR-T cell therapy has been one of the biggest breakthroughs in cancer medicine. By reprogramming a patient's own immune cells to attack cancer, doctors have produced remarkable results against certain ...
Aug 16, 2026
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