Immunology

Holes in the immune system left unrepaired despite drug therapy

If they don't receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system. But a very small percentage of patients—0.3%—spontaneously control the virus themselves, without ...

HIV & AIDS

HIV: Reprogramming cells to control infection

Cells from the rare individuals who naturally control HIV infection have been the focus of investigation for nearly 15 years with the aim of elucidating their specific features. Following research on the ANRS CO21 CODEX and ...

Oncology & Cancer

New vaccine strategy boosts T-cell therapy

A promising new way to treat some types of cancer is to program the patient's own T cells to destroy the cancerous cells. This approach, termed CAR-T cell therapy, is now used to combat some types of leukemia, but so far ...

Obstetrics & gynaecology

High-risk pregnancy: The interferon effect

High-risk pregnancies occur frequently, and have multiple causes. It is estimated that 10 to 20 percent of pregnant women miscarry during their first trimester of pregnancy. Slow fetal growth may also arise as a result of ...

Diseases, Conditions, Syndromes

A near-fatal Valley Fever case opens doors to new treatment method

Of the 8,000 Californians who will contract Valley Fever this year, most will recover without treatment, and those with more serious cases will require an antifungal medication that clears the infection. But a few will experience ...

Diseases, Conditions, Syndromes

Researchers survey immune molecules found inside mycetoma lesions

Mycetoma is a common neglected disease caused by either fungi or bacteria which organize themselves into grains—areas of inflammation surrounded by a collagen capsule. Now, researchers reporting in PLOS Neglected Tropical ...

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