Scientists have discovered a new protective communication circuit between specialized immune cells in the intestines, a circuit that may be therapeutically targeted to improve inflammatory bowel disease outcomes, according ...
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In a new study published in Science Immunology, researchers at King's College London looked at a type of tissue important for the immune response called gut-associated lymphoid tissue (GALT), which is located within the lining ...
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For decades, influenza vaccines have been judged largely by the antibodies they generate in the bloodstream, a measure that has remained the gold standard since the first flu immunizations were administered in the 1940s.
About 25 million people in the U.S.—roughly eight out of 100—are diagnosed with asthma. Allergens, air pollution, extreme weather conditions and other irritants can cause chronic lung inflammation, leading to coughing, wheezing ...
Jun 15, 2026
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An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify ...
Jun 15, 2026
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Researchers at the University of Maryland School of Medicine (UMSOM) have identified a target that may improve the response to CAR T-cell therapy, a treatment for patients with recurrent or difficult-to-treat blood cancers.
Jun 15, 2026
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A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterize each cell type and those whose ...
Jun 15, 2026
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Dual-target CAR T-cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes ...
Jun 15, 2026
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Certain white blood cells in the immune system, known as neutrophils, can make cancer immunotherapy less effective, according to a new study from Karolinska Institutet published in the journal Immunity. The results show that ...
Jun 15, 2026
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Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first Phase III study of an in vivo CRISPR therapy. In this large-scale, double-blind trial, 80 patients with hereditary ...
Jun 15, 2026
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