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Immunology news

Neuroscience

Central nervous system-associated macrophages could modulate post-stroke immune responses

An ischemic stroke is a type of stroke that occurs when a blood clot in an artery, also known as thrombus, or the progressive narrowing of arteries, blocks the blood and oxygen flowing to the brain. This process can cause ...

Neuroscience

Building bridges between cells for brain health: Research finds microglia rescue neurons through tunneling nanotubes

The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew. A recent study conducted ...

Diseases, Conditions, Syndromes

Scientists identify key protein behind spread of shingles virus

Scientists at the University of Colorado Anschutz Medical Campus have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from ...

Immunology

T cells and aging: Unraveling the complexities of lifespan

Aging significantly impacts the immune system, notably through the involution of the thymus, which reduces T cell production. This decline weakens immune responses, making older adults more susceptible to infections and diseases. ...

Immunology

Newly identified immune cell switch could control inflammation

Cornell researchers have identified a switch that regulates inflammation caused by an immune response, a finding that could one day help clinicians control inflammation-related conditions such as autoimmune, cardiovascular ...

Alzheimer's disease & dementia

Unique neutrophil type associated with Alzheimer's disease identified

Researchers have identified a unique type of neutrophil significantly associated with Alzheimer's disease (AD) pathology and mapped the transcriptome of neutrophils in the peripheral blood of AD mice. The study was published ...

Oncology & Cancer

Blood test may guide use of multiple myeloma immunotherapy

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

Diseases, Conditions, Syndromes

Scientists pinpoint new drug target for RSV

Scientists have discovered how the dangerous respiratory syncytial virus (RSV) defuses our immune response and, in doing so, have pinpointed an exciting new target for drug developers.

Oncology & Cancer

Scientists develop potential stealth cancer therapy

Sneaking by cancer's defenses, by disguising tumor-fighting antibodies inside the molecules cancer uses to nourish tumor growth, is the basis of a novel therapy from Yale Cancer Center researchers at the Yale School of Medicine ...

Oncology & Cancer

Study reveals dual role of protein in cancer treatment

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering ...