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Immunology news

Immunology

Scientists develop 'suspended animation' technique for blood draws to aid research for underserved populations

Your blood is a delicate mixture. Researchers and clinicians often use blood to learn what's going on inside our bodies, in part because siphoning off a tube of blood is easier and less painful than taking biopsies of an ...

Oncology & Cancer

Novel screening tech enhances identification of cancer-targeting T cell receptors

Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and ...

Diseases, Conditions, Syndromes

Bile acids' surprising role in food allergy treatment revealed

Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers ...

Immunology

How a simple amino acid could shape immune response

A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.

Oncology & Cancer

Discovery of CAR-T 'memory cells' could boost cancer therapy

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other ...

Diseases, Conditions, Syndromes

T cells may offer some protection in an H5N1 'spillover' scenario

New research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on standby to fight the H5N1 virus, also known as highly pathogenic avian influenza.

Medical research

Study reveals macrophages' misunderstood role in lung fibrosis

Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as "pro-fibrotic" ...

Oncology & Cancer

Q&A: Interplay between immune cells and HPV keeps skin healthy

Shadmehr (Shawn) Demehri, MD, Ph.D., of the Department of Dermatology and Center for Cancer Immunology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Cell, "Commensal papillomavirus ...

Oncology & Cancer

Why copper could be key to treating a rare childhood cancer

The survival rate for children with a rare but deadly cancer could one day be improved by adding an existing drug—which is currently used to manage excess copper in the body—to their treatment.

Genetics

New drug strategy targets rare immune disorders' genetic roots

Several rare immune disorders are caused by mutations in the patient's DNA. In a new study published in the Journal of Clinical Immunology, the University of Surrey and its collaborators found that targeting the mutated pathways ...

Oncology & Cancer

How chemotherapy primes ovarian cancer for immune-based therapies

Researchers have discovered how chemotherapy can change tumors, making them more vulnerable to new types of treatments. These findings could lead to personalized therapies that target the right patients at the right time, ...

Oncology & Cancer

New treatment may delay cancer in high-risk myeloma

A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood ...