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Immunology news

Immunology

Fever drives enhanced activity and mitochondrial damage in a subset of T cells, study finds

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center ...

Oncology & Cancer

Identifying sex-based differences in immune responses against tumors

Researchers at Saint Louis University School of Medicine investigated differences in T-cell responses between male and female patients with lung cancer that may help direct future treatments. T-cell responses are part of ...

Diseases, Conditions, Syndromes

Polio's last stand: The global fight for eradication

Poliomyelitis is an ancient disease that has resulted in significant morbidity and mortality worldwide for centuries. Its history is complicated by changes in the way humans adapt and live, and advancements in prevention ...

Oncology & Cancer

Lowering cancer drug dose could open tumors to immunotherapy

Research undertaken at the Harry Perkins Institute of Medical Research in Perth has shown that administering anti-cancer drugs at a hundred-fold lower dose than standard protocols could improve the tumor's response to immunotherapy.

Oncology & Cancer

From new treatments to AI: advances in the fight against cancer

From combining treatments in unprecedented ways to deploying artificial intelligence for personalized medicine, a raft of new advances in the fight against cancer have been presented at the European Society for Medical Oncology ...

Oncology & Cancer

Reprogramming cancer cells to attack themselves

A team of health and medical researchers affiliated with a host of institutions across Sweden has tested the possibility of reprogramming cancer cells into cDC1 cells as a means for destroying the protective shield around ...

Oncology & Cancer

New multimodal signature could predict immunotherapy success

An international team of researchers led by Francesca Finotello from the Digital Science Center (DiSC) and the Department of Molecular Biology has derived a molecular signature from tumor transcriptomics data that quantifies ...

Oncology & Cancer

Cancer cells may be using lipids to hide from the immune system

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's defenses can swoop in, destroying ...

Diseases, Conditions, Syndromes

Discovery could help treat fatal, drug-resistant pneumonia and sepsis

Bacterial pneumonia and sepsis are leading causes of hospitalization and death. Researchers in Kansas State University's Division of Biology have discovered that dysfunction of the body's immune response to bacterial infection ...

Diseases, Conditions, Syndromes

Uncovering the specialized immune cells that fight COVID-19

Vaccines work by equipping our immune systems to fight an invading virus. When we get vaccinated against COVID-19, specialized immune cells known as B cells learn to recognize the virus. If we subsequently get infected with ...