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Immunology news
Immunology
Fever drives enhanced activity and mitochondrial damage in a subset of T cells, study finds
Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center ...
37 minutes ago
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Oncology & Cancer
Identifying sex-based differences in immune responses against tumors
Researchers at Saint Louis University School of Medicine investigated differences in T-cell responses between male and female patients with lung cancer that may help direct future treatments. T-cell responses are part of ...
49 minutes ago
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Researchers discover immune response to dengue can predict risk of severe reinfections
As the dengue virus continues to be a significant global health concern, an international research team led by Duke-NUS Medical School has identified a critical link between the body's initial immune response and its defense ...
2 hours ago
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Study: Inflammatory cells in tumor microenvironment transform prostate cancer cells into treatment-resistant cells
Treatment-resistant cells are a challenge related to prostate cancer and many other cancers, which arises as the disease progresses. However, these resistance mechanisms are not yet fully understood.
1 hour ago
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New combination treatment brings hope to patients with advanced bladder cancer
Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer. The results, published ...
22 hours ago
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Polio's last stand: The global fight for eradication
Poliomyelitis is an ancient disease that has resulted in significant morbidity and mortality worldwide for centuries. Its history is complicated by changes in the way humans adapt and live, and advancements in prevention ...
22 hours ago
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Immune cells linked to blood vessel damage and neurodegeneration
A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer's disease—increases the risk of neurodegeneration and white matter damage.
Sep 19, 2024
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Low oxygen levels in tumors could enhance some of the body's immune responses against cancer
In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia. Hypoxia arises as tumors grow rapidly, outpacing their blood supply due to the ...
Sep 19, 2024
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As blood cancer treatments evolve, so does the patient journey
Treatment for blood cancers is advancing, giving more options to people living with the disease.
Sep 19, 2024
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Scientists discover proteins in meat, milk and other foods suppress gut tumors
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative medical sciences (IMS) in Japan have discovered that food antigens like milk proteins help keep tumors from growing in our guts, specifically the small intestines. ...
Sep 18, 2024
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Antiviral-resistant variants of SARS-CoV-2 can emerge in immunocompromised people
Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population found researchers at Weill ...
Sep 18, 2024
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Lowering cancer drug dose could open tumors to immunotherapy
Research undertaken at the Harry Perkins Institute of Medical Research in Perth has shown that administering anti-cancer drugs at a hundred-fold lower dose than standard protocols could improve the tumor's response to immunotherapy.
Sep 18, 2024
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Bacterial infections could be trigger for type 1 diabetes, new research suggests
For the first time, scientists have found that proteins from bacteria can trigger the immune system to attack insulin-producing cells, leading to the development of type 1 diabetes.
Sep 18, 2024
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Researchers identify role of Parkinson's-related protein in cancer and T cell activation
A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson's disease—in the body's innate immune response to cancer. Parkin is not expressed in several cancers.
Sep 18, 2024
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Exploring the effect of low sodium concentrations on brain microglial cells
Low serum sodium concentrations in the blood are called hyponatremia, a prevalent clinical electrolyte disorder. In contrast to acute hyponatremia, chronic hyponatremia has been previously considered asymptomatic because ...
Sep 18, 2024
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Team demonstrates unprecedented control of SIV replication with immune-based approach
Emory researchers are the first to show unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The success ...
Sep 17, 2024
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Research suggests many people already have T cells with the power to fight avian flu
Research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on "stand by" to fight the H5N1 virus, also known as highly pathogenic avian influenza.
Sep 17, 2024
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Study sheds light on how virus-fighting cells develop during long COVID
A new long-term study into long COVID has investigated how a certain population of white blood cells, called memory T cells, are established and develop as part of the body's defense to fight off the disease.
Sep 17, 2024
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Critical immune factor for host defense against MRSA offers potential explanation for unsuccessful vaccine strategies
Staphylococcus aureus, mostly known from its antibiotic-resistant variant methicillin-resistant Staphylococcus aureus (MRSA), is among the leading causes of both community- and hospital-acquired infections. According to the ...
Sep 17, 2024
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New research could lead to better treatment for oral cancer
Macquarie University researchers have discovered new information about how oral cancer cells may block the body's immune response. This could lead to better treatments for this aggressive disease.
Sep 17, 2024
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From new treatments to AI: advances in the fight against cancer
From combining treatments in unprecedented ways to deploying artificial intelligence for personalized medicine, a raft of new advances in the fight against cancer have been presented at the European Society for Medical Oncology ...
Sep 17, 2024
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A new way to reprogram immune cells and direct them toward anti-tumor immunity
A collaboration between four MIT groups, led by principal investigators Laura L. Kiessling, Jeremiah A. Johnson, Alex K. Shalek, and Darrell J. Irvine, in conjunction with a group at Georgia Tech led by M.G. Finn, has revealed ...
Sep 16, 2024
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Reprogramming cancer cells to attack themselves
A team of health and medical researchers affiliated with a host of institutions across Sweden has tested the possibility of reprogramming cancer cells into cDC1 cells as a means for destroying the protective shield around ...
Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer, clinical trial finds
Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the ...
Sep 16, 2024
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Monoclonal antibodies offer hope for tackling antimicrobial resistance
Monoclonal antibodies—treatments developed by cloning a cell that makes an antibody—could help provide an answer to the growing problem of antimicrobial resistance, say scientists.
Sep 16, 2024
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