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Immunology news

Diseases, Conditions, Syndromes

Immune-targeted approach helps control tuberculosis in mice

Mice infected with the bacteria that cause tuberculosis (TB) fared better when treated with an experimental compound that modulates immune responses than untreated mice did, according to a study led by Christina Stallings, ...

Immunology

Researchers reveal how psychological stress may aggravate skin allergies

Psychological stress is known to exacerbate skin allergies, but the underlying molecular mechanisms remain poorly understood.

Diseases, Conditions, Syndromes

Gene therapy could treat chronic hypereosinophilia

A study published in Human Gene Therapy has involved the generation of a human monoclonal antibody (mAb) directed against human eosinophils. The heavy and light chains of that fully human anti-human eosinophil mAb were delivered ...

Diseases, Conditions, Syndromes

Bile acids' surprising role in food allergy treatment revealed

Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers ...

Immunology

How a simple amino acid could shape immune response

A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.

Oncology & Cancer

Discovery of CAR-T 'memory cells' could boost cancer therapy

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other ...

Diseases, Conditions, Syndromes

T cells may offer some protection in an H5N1 'spillover' scenario

New research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on standby to fight the H5N1 virus, also known as highly pathogenic avian influenza.

Medical research

Study reveals macrophages' misunderstood role in lung fibrosis

Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as "pro-fibrotic" ...

Obstetrics & gynaecology

Fetal defense: Study reveals early immune protection in the womb

Research from Duke-NUS Medical School has revealed that fetuses are not as defenseless as once thought; they can actually fight infections from within the womb. This new understanding could significantly change the way doctors ...

Oncology & Cancer

Study links high-fiber diet to delayed progression of blood cancer

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have reported results from the first-ever clinical trial demonstrating that a high-fiber, plant-based dietary intervention may delay progression to multiple myeloma, ...

Oncology & Cancer

Keto diet metabolite may power up CAR T cells to kill cancer

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer ...

Immunology

Engineered immune cells may be able to tame inflammation

When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. But now, scientists at UC San Francisco may have found a more ...

Oncology & Cancer

Anticancer drugs could make immunotherapies more effective

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

Diseases, Conditions, Syndromes

How SARS-CoV-2 exploits human proteins to replicate

Researchers at Karolinska Institutet have discovered how the SARS-CoV-2 virus, which causes COVID-19, manipulates human proteins to replicate and evade the immune system. The results have been published in Nature Communications.

Immunology

Developing a chip to measure immunity

Every winter, influenza returns with a new variant. People who have previously been infected with or vaccinated against flu may have some protection, but this depends on how well their immune system's "memory" of the previous ...