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Allergy and immunology news

Why the body's inflammatory alarm misfires in familial Mediterranean fever

Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation. ...

Early respiratory infections linked to atopic dermatitis diagnosis

Early respiratory infection burden is associated with atopic dermatitis (AD) diagnosis in childhood, according to a study published online July 29 in JAMA Dermatology.

Researchers discover immune 'off switch' used by cancer cells

Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective.

A high-sugar diet may worsen asthma, even in the short term

Sugar consumption has been linked to an increased risk of cavities and weight gain. In the long term, it may also contribute to insulin resistance and diabetes. For people living with asthma, however, the impact can be even ...

Leaky gut might make food allergies worse

A "leaky gut" might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology. The researchers found that changes to the gut microbiome in mice were linked ...

Key gut protein balances immune protection and tolerance

A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates ...

How immune cells in our gut mesentery fight salmonella

Widely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets, and in unpasteurized dairy products. If untreated, extreme cases can lead to full-body infections, like typhoid fever. ...

Study reveals a distinct subtype of eosinophilic esophagitis

Researchers from Ann & Robert H. Lurie Children's Hospital of Chicago identified a distinct subtype of eosinophilic esophagitis (EoE)—a chronic allergic inflammatory disorder in which the esophagus narrows, interfering with ...

Resetting psoriasis memory may help body stop repeat flare-ups

Stress, bad weather, strep throat, alcohol or cuts—there are a number of triggers that can set off psoriasis. At the same time, a great deal is happening in research on this skin disease, and new ways of controlling the immune ...