Last update:
Immunology news
Diseases, Conditions, Syndromes
Kidney disease compromises survival of infection-fighting cells, study reveals
Fighting off infections when one has a chronic disease is a common problem, and during the COVID-19 pandemic that scenario often turned out to be dangerous and deadly. A new study led by Stony Brook Medicine demonstrates ...
19 hours ago
0
0
Oncology & Cancer
Macrophages, not T cells, may hold key to predicting which melanoma patients are more likely to respond to immunotherapy
An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that engulf pathogens and cancer cells—can be used to predict whether or not a melanoma patient ...
16 hours ago
0
0
Immune-targeted approach helps control tuberculosis in mice
Mice infected with the bacteria that cause tuberculosis (TB) fared better when treated with an experimental compound that modulates immune responses than untreated mice did, according to a study led by Christina Stallings, ...
Jan 7, 2025
0
0
Researchers reveal how psychological stress may aggravate skin allergies
Psychological stress is known to exacerbate skin allergies, but the underlying molecular mechanisms remain poorly understood.
Jan 7, 2025
0
1
Gene therapy could treat chronic hypereosinophilia
A study published in Human Gene Therapy has involved the generation of a human monoclonal antibody (mAb) directed against human eosinophils. The heavy and light chains of that fully human anti-human eosinophil mAb were delivered ...
Jan 7, 2025
0
0
Scientists develop 'suspended animation' technique for blood draws to aid research for underserved populations
Your blood is a delicate mixture. Researchers and clinicians often use blood to learn what's going on inside our bodies, in part because siphoning off a tube of blood is easier and less painful than taking biopsies of an ...
Jan 6, 2025
0
55
Novel screening tech enhances identification of cancer-targeting T cell receptors
Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and ...
Jan 6, 2025
0
27
Bile acids' surprising role in food allergy treatment revealed
Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers ...
Jan 6, 2025
0
5
Discovery of immune-boosting fibroblasts offers hope for cancer patients
Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective.
Jan 6, 2025
0
0
Exploring IL-8⁺ neutrophils and their role in severe alcohol-associated hepatitis
Alcohol-associated hepatitis (AH) is a critical global health issue characterized by acute liver inflammation and an elevated risk of mortality in its severe form (sAH). While the condition has been studied extensively, effective ...
Jan 6, 2025
0
0
Scientists unveil surprising human vs. mouse differences in a major cancer immunotherapy target
Since its discovery in the 1990s, programmed cell death protein 1 (PD-1) has been regarded as a leading target in cancer treatments. A checkpoint receptor that often resides on the surface of immune system cells, the PD-1 ...
Jan 3, 2025
0
63
How a simple amino acid could shape immune response
A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Jan 3, 2025
0
101
Novel class of anti-malaria antibodies could lead to next-generation interventions
A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study by researchers at the National Institutes of Health (NIH) published ...
Jan 3, 2025
0
51
FDA approves subcutaneous opdivo qvantig for most solid tumor indications
The U.S. Food and Drug Administration has approved Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) injection for subcutaneous use for most previously approved adult, solid tumor Opdivo (nivolumab) indications.
Jan 3, 2025
0
0
Discovery of CAR-T 'memory cells' could boost cancer therapy
Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other ...
Jan 2, 2025
0
24
Blood test can predict how long vaccine immunity will last, study shows
When children receive their second measles-mumps-rubella vaccine, around the time they start kindergarten, they gain protection against all three viruses for all or most of their lives. Yet the effectiveness of an influenza ...
Jan 2, 2025
0
70
Microglia digest large Alzheimer's plaques by spitting enzymes at them, preclinical study finds
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing digestive enzymes into ...
Jan 2, 2025
0
36
T cells may offer some protection in an H5N1 'spillover' scenario
New research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on standby to fight the H5N1 virus, also known as highly pathogenic avian influenza.
Jan 2, 2025
0
16
Researchers find potential link between nuclear speckles patterns and cancer treatment outcomes
Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why. Now, Cold Spring ...
Jan 2, 2025
0
27
Clinical trial shows cancer-preventing topical immunotherapy trains immune system to fight precancers
A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment. This therapy is the first to activate specific ...
Jan 2, 2025
0
0
Targeting tristetraprolin in basophils: Researchers find promising therapeutic target for allergic inflammation
Inflammation is a crucial part of the body's defense mechanism, playing a key role in fighting infections and repairing tissue damage. Basophils, a type of immune cell that makes up less than 1% of white blood cells, have ...
Jan 2, 2025
0
0
Scientists link hematopoietic cell transplant deaths to beta-blocker use
Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration.
Dec 31, 2024
0
55
Study reveals macrophages' misunderstood role in lung fibrosis
Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as "pro-fibrotic" ...
Dec 27, 2024
0
59
Bidirectional association found between rheumatoid arthritis, COPD
There is a bidirectional association between rheumatoid arthritis (RA) and chronic obstructive pulmonary disease (COPD), according to a review published online Dec. 1 in Frontiers in Immunology.
Dec 27, 2024
0
0
FDA approves Ryoncil for steroid-refractory acute graft-versus-host after allo-HSCT
The allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy Ryoncil (remestemcel-L-rknd) has been approved for treatment for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients ...
Dec 27, 2024
0
0
