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Immunology news
HIV & AIDS
Team demonstrates unprecedented control of SIV replication with immune-based approach
Emory researchers are the first to show unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The success ...
16 hours ago
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Diseases, Conditions, Syndromes
Study sheds light on how virus-fighting cells develop during long COVID
A new long-term study into long COVID has investigated how a certain population of white blood cells, called memory T cells, are established and develop as part of the body's defense to fight off the disease.
22 hours ago
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Critical immune factor for host defense against MRSA offers potential explanation for unsuccessful vaccine strategies
Staphylococcus aureus, mostly known from its antibiotic-resistant variant methicillin-resistant Staphylococcus aureus (MRSA), is among the leading causes of both community- and hospital-acquired infections. According to the ...
23 hours ago
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New research could lead to better treatment for oral cancer
Macquarie University researchers have discovered new information about how oral cancer cells may block the body's immune response. This could lead to better treatments for this aggressive disease.
17 hours ago
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Research suggests many people already have T cells with the power to fight avian flu
Research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on "stand by" to fight the H5N1 virus, also known as highly pathogenic avian influenza.
Sep 17, 2024
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From new treatments to AI: advances in the fight against cancer
From combining treatments in unprecedented ways to deploying artificial intelligence for personalized medicine, a raft of new advances in the fight against cancer have been presented at the European Society for Medical Oncology ...
Sep 17, 2024
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A new way to reprogram immune cells and direct them toward anti-tumor immunity
A collaboration between four MIT groups, led by principal investigators Laura L. Kiessling, Jeremiah A. Johnson, Alex K. Shalek, and Darrell J. Irvine, in conjunction with a group at Georgia Tech led by M.G. Finn, has revealed ...
Sep 16, 2024
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Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer, clinical trial finds
Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the ...
Sep 16, 2024
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Reprogramming cancer cells to attack themselves
A team of health and medical researchers affiliated with a host of institutions across Sweden has tested the possibility of reprogramming cancer cells into cDC1 cells as a means for destroying the protective shield around ...
Monoclonal antibodies offer hope for tackling antimicrobial resistance
Monoclonal antibodies—treatments developed by cloning a cell that makes an antibody—could help provide an answer to the growing problem of antimicrobial resistance, say scientists.
Sep 16, 2024
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Mucin gel may help disk herniation patients after surgery
Researchers at Uppsala University have developed a gel inspired by cow slime for patients suffering from disk herniation. By adding the mucin gel immediately after surgery, it is possible to create a protective barrier around ...
Sep 16, 2024
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Immunotherapy shows promise for men with specific types of prostate cancer
New research has shown that immunotherapy can be effective in treating prostate cancer in men who are selected based on the genetic characteristics of their tumors.
Sep 16, 2024
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Cloning several new anti-interferon antibodies to develop future therapeutic candidates
New research from The Wistar Institute's Montaner lab—led by Wistar Executive Vice President, director of the HIV Cure and Viral Disease Center, and Herbert Kean, M.D., Family Professor, Luis Montaner, D.V.M., D.Phil.—has ...
Sep 16, 2024
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Gynecological cancers: Immunotherapy and targeted drug appear beneficial in group of women with early-stage disease
Studies reported at ESMO 2024 reveal new groups of women with early-stage endometrial and cervical cancers who gain clinically meaningful benefit from adding immunotherapy to current standard treatments, while a first-in-human ...
Sep 16, 2024
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Studies show immunotherapy improves long-term survival in growing number of cancers
Immunotherapy, which works by enabling the body's immune system to recognize and destroy cancer cells improves long-term overall survival in patients with advanced melanoma in results from large international studies reported ...
Sep 16, 2024
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Long-term metastatic melanoma survival dramatically improves on immunotherapy, clinical trial finds
Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new ...
Sep 15, 2024
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Your gas stove might be making your asthma worse: What you can do about it
We may think of air pollution as an outdoor problem, made up of car exhaust and smog. But if the air inside our homes is polluted, this can also affect our health.
Sep 14, 2024
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Study finds 'supercharging' T cells with mitochondria enhances their antitumor activity
Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in ...
Sep 13, 2024
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Neoself-antigens found to induce autoimmune response in lupus
Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood.
Sep 13, 2024
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Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer
A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. ...
Sep 13, 2024
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Experimental mRNA cancer vaccine shows potential for advanced stage cancer patients in Phase I trial
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.
Sep 13, 2024
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How the immune system fails as cancer arises
Cancer has been described as "a wound that does not heal," implying that the immune system is unable to wipe out invading tumor cells. A new discovery confirms that a key molecule can reprogram immune cells that normally ...
Sep 12, 2024
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Study identifies five key factors that predict response of cancer patients to immunotherapy
A team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients' response to checkpoint inhibitors (CPIs). The study, which has been published in Nature Genetics, validates these ...
Sep 12, 2024
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Triple antibody therapy shows promise for long-lasting HIV control
In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with ...
Sep 12, 2024
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Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer
Researchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patients. The findings, published ...
Sep 12, 2024
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