PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations
In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced ...
Cancer
May 15, 2013 |
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Are human genes patentable?
(Medical Xpress)—On April 15, the Supreme Court will hear oral argument in Association for Molecular Pathology v. Myriad Genetics, a case that could answer the question, "Under what conditions, if any, ...
Genetics
Apr 11, 2013 |
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Nearly half of breast cancer patients at risk of having BRCA mutations not sent for genetic testing
Only 53 percent of newly diagnosed breast cancer patients who were at high risk of carrying a BRCA 1 or BRCA 2 mutation – based on age, diagnosis, and family history of breast or ovarian cancer – reported that their doctors ...
Cancer
Apr 08, 2013 |
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Gene mutation's benefit for ovarian cancer patients may not last: study
(HealthDay)—Although women diagnosed with ovarian cancer who carry a BRCA gene mutation have a short-term survival advantage, this benefit is not reflected in the long-term, according to a new study.
Cancer
Feb 20, 2013 |
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Early menopause may occur in women with BRCA gene, study finds
Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even ...
Cancer
Jan 29, 2013 |
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New test predicted presence of harmful BRCA mutations
A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a jour ...
Cancer
Jan 22, 2013 |
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Study reveals young women with the BRCA mutation feel different and misunderstood
(Medical Xpress)—A study authored by Rebekah Hamilton, RN, PhD, associate dean of the Rush University College of Nursing, found that young women with a BRCA1 and BRCA2 gene mutation felt different and misunderstood.
Cancer
Sep 26, 2012 |
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BRCA1 or BRCA2 mutation research may offer treatment option to certain patients
(Medical Xpress)—Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an ...
Cancer
Sep 20, 2012 |
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Gene inheritance patterns influence age of diagnosis in BRCA families
Women who inherit the cancer genes BRCA1 or BRCA2 from their paternal lineage may get a diagnosis a decade earlier than those women who carry the cancer genes from their mother and her ancestors, according to a new study ...
Cancer
Dec 12, 2011 |
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Early detection is key in the fight against ovarian cancer
Ovarian cancer is a rare but often deadly disease that can strike at any time in a woman's life. It affects one in 70 women and in the past was referred to as a silent killer, but researchers have found there are symptoms ...
Cancer
Sep 15, 2011 |
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Women who inherit BRCA gene mutations develop cancer earlier than their ancestors
Women with a deleterious gene mutation are diagnosed with breast cancer almost eight years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The ...
Cancer
Sep 12, 2011 |
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Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Cancer
Aug 21, 2011 |
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Mismatch between cancer genetics counseling and testing guidelines and physician practices
A new analysis has found that many doctors report that they do not appropriately offer breast and ovarian cancer counseling and testing services to their female patients. Published early online in CANCER, a peer-reviewed journa ...
Cancer
Jul 25, 2011 |
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Women with BRCA mutations can take hormone-replacement therapy safely after ovary removal
Women with the BRCA1 or BRCA2 gene mutations, which are linked to a very high risk of breast and ovarian cancer, can safely take hormone-replacement therapy (HRT) to mitigate menopausal symptoms after surgical removal of ...
Cancer
Jun 01, 2011 |
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Researchers discover link between obesity gene and breast cancer
New research aimed to better identify the genetic factors that lead to breast cancer has uncovered a link between the fat mass and obesity associated gene (FTO) and a higher incidence of breast cancer. According to the study ...
Cancer
May 23, 2011 |
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