Researchers capture major chemotherapeutic target in complex with DNA damage
A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other ...
Medical research
May 10, 2012 |
4.7 / 5 (3) |
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Study: No difference in results by race with standard heart failure treatment
A traditional treatment for heart failure appears to be equally protective in preventing death or hospitalization among African-American patients, as compared to white patients, according to a study at Henry Ford Hospital ...
Cardiology
May 09, 2012 |
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Gene-modified stem cell transplant protects patients from toxic side effects of chemotherapy
For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients' own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of ...
Cancer
May 09, 2012 |
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Researchers identify drivers of sarcoma growth and survival
To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...
Cancer
May 02, 2012 |
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Advanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.
Cancer
Apr 26, 2012 |
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Study identifies gene critical to development and spread of lung cancer
A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may ...
Cancer
Apr 24, 2012 |
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Liver tells all and reveals truth about fat
Dr Barbara Fam from the University's Molecular Obesity Laboratory group at Austin Health with Associate Professor Sof Andrikopoulos have discovered that the liver can directly talk to the brain to control the amount of food ...
Diabetes
Apr 20, 2012 |
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Study identifies potential treatment for lethal childhood leukemia
Columbia University Medical Center (CUMC) scientists have demonstrated that two related enzymes — phosphoinositide-3 kinase (PI3K) gamma and delta — play a key role in the development of T-cell acute lymphoblastic ...
Cancer
Apr 16, 2012 |
5 / 5 (1) |
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New research could lead to better treatments for cardiovascular disease
Scientists at the University of Southampton have discovered a new process that controls the ability of arteries to regulate blood pressure.
Cardiology
Apr 03, 2012 |
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Scientists identify new mechanism of prostate cancer cell metabolism
Cancer cell metabolism may present a new target for therapy as scientists have uncovered a possible gene that leads to greater growth of prostate cancer cells.
Cancer
Mar 22, 2012 |
5 / 5 (4) |
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Disabling cancer cells' defenses against radiation
Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation.
Cancer
Mar 15, 2012 |
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New study unravels mystery of a DNA repair process
(Medical Xpress) -- Scientists at the University of Sussex have uncovered the mechanism of a key process in DNA repair that helps prevent neurodegenerative diseases such as ataxia.
Medical research
Mar 14, 2012 |
5 / 5 (1) |
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Calcium, vitamin D modulate human energy metabolism
(HealthDay) -- There is considerable evidence that calcium and vitamin D intake are influential in modulating energy metabolism in humans, according to a study published online March 2 in Obesity Reviews.
Health
Mar 12, 2012 |
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A lifetime of research may be leading to a life-saving treatment for shock
A 200-patient Phase 2 clinical pilot study will be initiated this month to test the efficacy and safety of a new use, and method of administering, an enzyme inhibitor for critically ill patients developed by University of ...
Medical research
Mar 12, 2012 |
5 / 5 (3) |
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Studies show that CYP2D6 genotype does not predict tamoxifen benefit
Two studies published March 6 in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the us ...
Cancer
Mar 06, 2012 |
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