News tagged with oncogene

Related topics: cancer cells · breast cancer · tumor · cancer · tumor cells

NTRK1: A new oncogene and target in lung cancer

To the list of oncogenic drivers of lung cancer that includes ALK, EGFR, ROS1 and RET, results of a University of Colorado Cancer Center study presented at ASCO 2013 show that mutations in the gene NTRK1 cause a subset of ...

Jun 03, 2013
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New factor to control oncogene-induced senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene ...

May 21, 2013
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An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.

Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.

This text uses material from Wikipedia, licensed under CC BY-SA

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