News tagged with oncogene
Related topics: cancer cells , breast cancer , tumor , cancer , tumor cells
An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.
Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.
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An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induce ...
Cancer May 21, 2013 | not rated yet | 0
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. ...
Cancer May 06, 2013 | not rated yet | 0