Elevated levels of p-tau 181 and 217 in cerebrospinal fluid are considered to reflect early Alzheimer's disease pathology. However, biomarker detection, which is now part of the diagnostic criteria, requires a lumbar puncture ...
Mar 5, 2025
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Women who exhibit more menopausal symptoms are more likely to later have poorer cognitive function and mild behavioral impairments—both markers of dementia. That is the conclusion of a study of 896 postmenopausal females ...
Mar 5, 2025
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The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of the notorious tau protein, which can contribute to Alzheimer's and related diseases.
Mar 5, 2025
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Technology is changing how physicians think about assessing patients, and in turn, how patients expect to be able to measure their own health. Apps designed for smartphones and wearable devices can provide unique insights ...
Mar 4, 2025
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Studies reveal that people with Down syndrome (DS) have over a 90% lifetime risk of developing dementia caused by Alzheimer's disease (AD) as they age. Research from the University of Pittsburgh's Swanson School of Engineering ...
Mar 1, 2025
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A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells (iPSCs), the international team ...
Feb 28, 2025
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Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs. Breathing in wildfire smoke or automobile-related city smog doesn't just increase the risk of asthma and heart ...
Feb 27, 2025
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What if a critical piece of the puzzle of brain aging has been hiding in plain sight? While neuroscience has long focused on proteins and DNA, a team of Stanford researchers dared to shift their gaze to sugars—specifically ...
Feb 27, 2025
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Catholic nuns don't make a habit of participating in long-term studies on aging and dementia, but one notable exception has yielded critical insights into cognitive resilience, neuropathology and aging-related disorders.
Feb 26, 2025
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Protein accumulations do important work in the human body, but something can go wrong and proliferate in those aggregates, resulting in neurodegeneration and diseases such as Parkinson's and Alzheimer's.
Feb 26, 2025
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