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Laboratory medicine news

Common blood storage bags may leach microplastics into stored blood

In the 1970s, PVC bags revolutionized the storage of blood and blood products for transfusion. Disposable plastic (PVC) bags replaced reusable glass bottles, making the process more convenient and safer from contamination. ...

Closing the gap between suspecting a heart attack and confirming it

A person having a heart attack may be only feet from medical care but miles from the laboratory testing needed to confirm it. That gap matters, especially for rural patients, those in nursing homes, ambulances and other places ...

Blood marker tracks hidden progression in multiple sclerosis

Modern therapies have transformed care for people with multiple sclerosis (MS). Yet the disease continues to progress in a substantial proportion of patients, even in the absence of relapses. Detecting and treating this gradual ...

Warm nights linked to ill premature babies in NICUs

Premature babies in the intensive care unit are particularly at risk of becoming infected with potentially pathogenic bacteria. A team of doctors in Hanover has now investigated which external factors play a role in this. ...

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...

How a louse-borne pathogen evades the immune system

Louse-borne relapsing fever is caused by the spirochete bacterium Borrelia recurrentis, which is transmitted by body lice (not head lice). The disease was first described by Hippocrates (460–370 B.C.). Initial symptoms include ...