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Laboratory medicine news

Mapping human bone marrow yields new tool, insights on blood cancer

Weill Cornell Medicine investigators have developed a new AI-based method to assess patients with a form of blood cancer called myelodysplastic neoplasms. The method, published June 30 in Leukemia, compares the physical locations ...

DNA blood test improves patient selection for radiopharmaceutical therapy in prostate cancer

A noninvasive DNA blood test can identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are most likely to benefit from 223Ra radiopharmaceutical therapy and monitor their progress throughout treatment, ...

Warm nights linked to ill premature babies in NICUs

Premature babies in the intensive care unit are particularly at risk of becoming infected with potentially pathogenic bacteria. A team of doctors in Hanover has now investigated which external factors play a role in this. ...

Hepatitis E viruses mutate early during infection

Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability. Researchers from the Departments of Molecular & Medical Virology and Translational & Computational ...

Epigenetic mapping provides deeper insight into leukemia

Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood cancer acute myeloid leukemia. The study, published in the journal Nature, shows that changes in the ...

New brush test detects oral cancer in one hour

A paper published in the journal Biomarker Research by a cross-university team led by Queen Mary University of London researchers validates the use of a noninvasive brush biopsy test that can detect oral cancer within one ...

Mpox immune test validated during Rwandan outbreak

An antibody test for the infectious disease mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting. The test, an IgG ELISA ...

HIV-seq tool finds active reservoir cells during therapy

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission. Historically, these ...

Cheek cells may provide clues to schizophrenia risk

A simple cheek swab could one day provide a quick and noninvasive diagnostic test for schizophrenia. A new study published in Science Advances has identified higher levels of two biological markers in the cheek swabs of patients ...

Tiled amplicon sequencing could transform tuberculosis care

When the COVID-19 pandemic was at its peak, and multiple variants were threatening lives around the world, scientists relied on a process called "tiled amplicon sequencing" to track the virus's spread. Now, an international ...

Gallbladder cancer could soon be detected in blood

Researchers at Tezpur University in Assam, India, working with scientists at the University of Illinois Urbana-Champaign, have identified distinct chemical signatures in blood that could help detect gallbladder cancer earlier. ...