Intercellular Signaling Peptides and Proteins - Medical News and Research Articles

Inflammatory disorders

AI-designed protein shows 50% greater anti-inflammatory effect in animal studies

A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing.

Dec 29, 2025

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Inflammatory disorders

Monoclonal antibody shows promising results for rare liver disease

A multicenter study led by UC Davis Health has tested a new treatment designed to improve care for people with a rare liver disease called primary sclerosing cholangitis. Researchers learned that an anti-inflammatory and ...

Dec 23, 2025

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Medical research

Netrin-1 disrupts hepatitis B virus attachment and internalization, offering new treatment path

Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not eliminate the virus, highlighting ...

Dec 23, 2025

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Immunology

A new strategy for immune tolerance: Engineered extracellular vesicles show promise

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific ...

Dec 22, 2025

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Medications

Natural protein drug may slow neuron death linked to Alzheimer's disease

Scientists at the University of Colorado Anschutz have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, ...

Dec 20, 2025

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Neuroscience

Inflammation-induced metabolic shifts linked to brain disorders

Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. A new study published online in the ...

Dec 19, 2025

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Immunology

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

mRNA vaccines, such as those used against COVID-19, are effective at generating antibody responses. These antibodies are produced through specialized immune structures called germinal centers, but until now it was not fully ...

Dec 17, 2025

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Oncology & Cancer

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.

Dec 16, 2025

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Oncology & Cancer

Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation

The first-in-human clinical phase I trial assessing the feasibility and safety of WDVAX, an immunostimulatory biomaterial-based cancer vaccine, in a cohort of 21 patients with stage 4 metastatic melanoma, was concluded with ...

Dec 15, 2025

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Vaccination

AI-engineered nasal spray antiviral platform developed to block flu and COVID-19

Respiratory viruses that have diverse strains and mutate rapidly, such as influenza and COVID-19, are difficult to block perfectly with vaccines alone. To solve this problem, KAIST's research team has successfully developed ...