The World Health Organization says the worst yellow fever outbreak in decades has killed 178 people in Angola.

The organization said Thursday that more than 450 people have been infected by the disease since the outbreak was first reported in December last year.

It has been described as the worst outbreak in 30 years and spread from the capital Luanda to six of the country's 18 provinces.

The WHO statement said that while 5.7 million people have been vaccinated against , there is a global vaccine shortage. Half of the severely infected patients die within 10 to 14 days if they do not receive treatment.

Yellow fever is spread by mosquitoes, most commonly the Aedes aegypti mosquito, the same species that spreads the Zika virus.