January 17, 2017

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Weekly diabetes drug provides similar benefits to daily version

Credit: CC0 Public Domain
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Credit: CC0 Public Domain

A weekly dipeptidyl peptidase-4 (DPP-4) inhibitor was just as effective at controlling type 2 diabetic patients' blood sugar as a daily DPP-4 inhibitor in a recent randomized clinical trial.

The drug, called omarigliptin, offers the prospect of a more convenient treatment for patients with diabetes.

"The observed glycaemic efficacy in the present study indirectly serves as further evidence of the feasibility of providing DPP-4 inhibition over the period of 1 week with a single once-weekly dose that is similar to that which can be achieved with daily administration," wrote the authors of the Diabetes, Obesity and Metabolism study.

More information: Ronald Goldenberg et al. Randomized clinical trial comparing the efficacy and safety of treatment with the once-weekly dipeptidyl peptidase-4 (DPP-4) inhibitor omarigliptin or the once-daily DPP-4 inhibitor sitagliptin in patients with type 2 diabetes inadequately controlled on m, Diabetes, Obesity and Metabolism (2017). DOI: 10.1111/dom.12832

Provided by Wiley

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