Genetics

Researchers unlock the secrets of liver regeneration

In a recent study published in the journal Developmental Cell, NYU Abu Dhabi researchers have reported a new way in which the liver is primed to regenerate itself. They found that by stripping parts of the epigenome, which ...

Genetics

Building new tools to study the epigenome

Researchers know that the epigenome plays a key role in how DNA is expressed, and have linked changes in the epigenome to a wide variety of health problems – from cancers to autoimmune disorders. But not only is there a ...

Genetics

Our epigenome is influenced by our habitat and lifestyle

Research on the genomes of Pygmy hunter-gatherer populations and Bantu farmers in Central Africa, carried out by scientists from the Institut Pasteur and the CNRS in cooperation with French and international teams, has shown ...

Immunology

Epigenomic changes are key to innate immunological memory

A research team led by Keisuke Yoshida and Shunsuke Ishii of the RIKEN Molecular Genetics Laboratory has revealed that epigenomic changes induced by pathogen infections, mediated by a transcription factor called ATF7, are ...

Genetics

Epigenome orchestrates embryonic development

The early stages of embryonic development shape our cells and tissues for life. It is during this time that our newly formed cells are transformed into heart, skin, nerve or other cell types. Scientists are finding that this ...

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Epigenome

Epigenome is equivalent to genome in epigenetics. Epigenetics is one of the current topics in cancer research drawing active research. Human tumors undergo a major disruption of DNA methylation and histone modification patterns. The aberrant epigenetic landscape of the cancer cell is characterized by a massive genomic hypomethylation, CpG island promoter hypermethylation of tumor suppressor genes, an altered histone code for critical genes and a global loss of monoacetylated and trimethylated histone H4.

Much of the subject matter is not yet fully understood. Some people have suggested a Human Epigenome Project.[citation needed]

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