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Arthritis & Rheumatism news

Arthritis & Rheumatism

Scientists urge earlier diagnosis and treatment of psoriatic arthritis to prevent permanent damage

Delays in diagnosing and treating psoriatic arthritis—a common inflammatory disorder affecting around 200,000 people in the U.K.—are causing irreparable damage to people's health. This damage could be avoided by catching ...

Arthritis & Rheumatism

Flexible hydrogel could improve drug delivery for post-traumatic osteoarthritis treatment

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms, but do not prevent or stop the progression of the condition. Although emerging therapies ...

Arthritis & Rheumatism

How might ACL surgery increase the risk of knee osteoarthritis?

Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes' knees, may develop early-onset knee osteoarthritis. A new study in the Journal of Orthopaedic ...

Arthritis & Rheumatism

Overactive bladder positively associated with arthritis

Overactive bladder (OAB) is associated with arthritis, with a positive association seen after adjustment for all covariates, according to a study published online Feb. 13 in Scientific Reports.

Arthritis & Rheumatism

Novel biomarker for rheumatoid arthritis revealed

Researchers have developed a novel analytical method for tracking disease progression in patients that shows great potential for health care implementation.

Alzheimer's disease & dementia

Rheumatoid arthritis tied to cognitive decline in dementia

A new Swedish study has, for the first time, shown a link between rheumatoid arthritis (RA) and cognitive decline in dementia patients. The study, published in the journal Neurology, emphasizes the importance of careful monitoring ...

Genetics

Study unveils 13 genes that increase the risk of osteoarthritis

Osteoarthritis is a painful condition in which cartilage—the protective cushioning between the joints—gradually breaks down. The progressive joint disease, which affects more than 32 million people in the United States, ...

Health

Researchers unlock predictive biomarkers for common hip disorder

Researchers from the University of Missouri School of Medicine have developed panels of protein biomarkers present in teens and young adults that distinguish individuals with healthy hips from those with developmental dysplasia ...

Medical research

New therapeutic target for osteoarthritis identified

Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature ...

Arthritis & Rheumatism

Understanding opioids in fibromyalgia

Fibromyalgia is common, affecting around 2% of people in the general population. The 2017 EULAR recommendations state that tramadol—a weak opioid—may be considered for pain management in fibromyalgia, but advise against ...

Diseases, Conditions, Syndromes

Liver function tests can ID occult disorders in systemic sclerosis

Liver function test (LFT) screening can identify occult hepatitis, cholestasis, and cholestatic hepatitis in patients with systemic sclerosis (SSc), according to a study published online May 2 in Open Access Rheumatology: ...

Neuroscience

Study investigates how fibromyalgia changes the brain

One of the core symptoms experienced by patients with fibromyalgia is chronic pain. A team from the LWL Clinic for Psychosomatic Medicine and Psychotherapy at Ruhr University Bochum, Germany, has investigated the brain changes ...

Arthritis & Rheumatism

Harmonizing rheumatology training across Europe

Postgraduate rheumatology training programs define the knowledge, skills, and behaviors needed for physicians to become specialists in rheumatology. In some countries there is a standardized approach, but in others the program ...

Arthritis & Rheumatism

TAp63: A new protein drug target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX). Many ...

Medications

Peresolimab found to be efficacious for rheumatoid arthritis

Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according ...

Arthritis & Rheumatism

New research sheds light on symptoms of understudied spine disease

After hearing firsthand from patients about how the disease impacted their lives, a team of researchers and graduate students at University of Western Ontario were inspired to investigate the symptoms associated with an understudied ...

Arthritis & Rheumatism

Does brepocitinib benefit patients with psoriatic arthritis?

Brepocitinib is an oral drug that inhibits certain enzymes involved in inflammation—called tyrosine kinase 2 and Janus kinase 1—and is being tested for the treatment of several immunological diseases. A phase IIb randomized ...