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Arthritis & Rheumatism news
Arthritis & Rheumatism
Scientist uncover hidden immune 'hubs' that drive joint damage in rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives. Yet, about one in three patients respond poorly to existing treatments.
Aug 15, 2025
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Diseases, Conditions, Syndromes
Lupus low disease activity state attainable in lupus nephritis
In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...
Aug 14, 2025
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How small changes in walking technique may help treat knee osteoarthritis
Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an incurable disease ...
Aug 12, 2025
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FDA approves SetPoint neuroimmune modulation device for rheumatoid arthritis
The U.S. Food and Drug Administration has approved the SetPoint System, a neuroimmune modulation device for the treatment of adults living with moderate-to-severe rheumatoid arthritis (RA).
Aug 8, 2025
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A low-calorie diet likely won't directly help hip osteoarthritis pain but could still have health benefits
A randomized controlled trial evaluated the efficacy of a weight-loss diet added to exercise on the change in hip pain among adults with hip osteoarthritis. The study found that adding a weight-loss diet did not change hip ...
Aug 5, 2025
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When immune commanders misfire: New insights into rheumatoid arthritis inflammation
Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage. Approximately 18 million people ...
Aug 1, 2025
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Progress in gene therapy offers hope for long-term knee pain relief
For nearly three decades, Mayo Clinic researcher Christopher Evans, Ph.D., has pushed to expand gene therapy beyond its original scope of fixing rare, single-gene defects. That has meant systematically advancing the field ...
Jul 30, 2025
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Ankles might point the way to cartilage repair in osteoarthritis
The ankle's ability to regenerate cartilage uses the same mechanisms that enable some animals to grow new limbs, and it could be harnessed to repair cartilage in knees and hips hobbled by osteoarthritis.
Jul 14, 2025
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Clinical test predicts best rheumatoid arthritis treatment on first try
1 in 100 people in Britain today live with rheumatoid arthritis (RA). Unlike osteoarthritis (OA), RA is caused not by wear and tear but by the body's immune system attacking its own joints. RA can strike quickly at any age—but ...
Jul 3, 2025
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Protein target could control chronic inflammation without affecting acute response
Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years. Diseases associated with chronic inflammation, like arthritis or ...
Jul 2, 2025
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Visualizing what happens in inflamed joints of children with arthritis could lead to possible new disease targets
A new study by researchers from the University of Birmingham, UCL, Great Ormond Street Hospital and Birmingham Children's Hospital has revealed important clues into what is driving disease in children with arthritis.
Jul 2, 2025
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Researchers find immune pathway in joint tissue involved in early rheumatoid arthritis
A new study by scientists at the University of Colorado Anschutz Medical Campus reveals that joint tissue from patients with early-stage rheumatoid arthritis often have high levels of a protein called granzyme used by the ...
Jul 2, 2025
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Novel form of exercise offers relief for people with rheumatoid arthritis
It's a debilitating disease that affects more than 500,000 Australians, but new research from the University of South Australia is offering fresh hope to people living with rheumatoid arthritis (RA).
Jul 1, 2025
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New insights into chronic inflammation in rheumatoid arthritis
Kennedy researchers have uncovered new clues about how immune memory exacerbates inflammation in rheumatoid arthritis, which could lead to better ways to control the disease.
Jun 30, 2025
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Malnutrition may be a hidden health factor for people with obesity and osteoarthritis
Malnutrition could be a hidden culprit that lowers quality of life for people with larger bodies, especially if they have a health condition like osteoarthritis, University of Alberta research has found.
Jun 26, 2025
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Simple therapies outperform high-tech options for knee arthritis pain and mobility
Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis published in PLOS One by Yuan Luo of the First People's Hospital of Neijiang, ...
Jun 18, 2025
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Genes may help to predict which children will respond well to arthritis treatment
A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) has been identified by researchers at UCL and Great Ormond Street Hospital for ...
Jun 17, 2025
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AI-powered study shows surge in global rheumatoid arthritis since 1980, revealing local hotspots
The most comprehensive analysis of rheumatoid arthritis data to date reveals that demographic changes and uneven health infrastructure have exacerbated the rheumatoid arthritis burden since 1980 and shows global disparities ...
Jun 16, 2025
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Integrative exome sequencing and machine learning identify new genes contributing to systemic sclerosis risk
Systemic sclerosis (SSc) is a severe autoimmune disease with complex genetic causes. Some genetic contributors have been identified, but others remain unknown, which has impeded development of targeted treatments. In a new ...
Jun 16, 2025
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The many ways that AI enters rheumatology
Artificial intelligence (AI) is entering the mainstream. The term encompasses a wide variety of machines that can learn from data, identify patterns, and make decisions. But how can it be used to support health care? EULAR—The ...
Jun 16, 2025
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Osteoarthritis: Too many non-evidence-based therapies?
Osteoarthritis is a leading cause of chronic pain, often affecting physical function, daily activities, and quality of life. EULAR—The European Alliance of Associations for Rheumatology—has developed recommendations and ...
Jun 13, 2025
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Exploring patient experiences in juvenile idiopathic arthritis
Adolescents and young adults with chronic diseases need special care—and pediatric rheumatological conditions can persist into adulthood. Two new works presented at the 2025 congress of EULAR—The European Alliance of ...
Jun 13, 2025
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Studies show nurses play a critical role for people with rheumatic musculoskeletal diseases
EULAR—The European Alliance of Associations for Rheumatology—believes that nurses are an important part of the health care team, especially for providing evidence-based care and endorsing shared decision-making in consultation ...
Jun 13, 2025
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Synergistic drug combinations explored for systemic sclerosis vasodilation
It is known that vasculopathy plays a pivotal role in the pathogenesis of systemic sclerosis (SSc). Vasoactive vasodilating drugs (VVD) are an option. The most recent treatment recommendations from EULAR—The European Alliance ...
Jun 13, 2025
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Study reveals risk factors for spinal deterioration in r-axSpA
Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic musculoskeletal disease that predominantly affects the axial skeleton. axSpA is an umbrella term that comprises the whole spectrum of patients with and without ...
Jun 13, 2025
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