MeSH tree: D12.776.124.050.070
Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This regulation is crucial, and ...
Apr 17, 2025
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Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency, new research shows. Alpha-1 antitrypsin deficiency (A1AD) is a genetic condition caused ...
Mar 10, 2025
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The treatment of patients with severe COVID-19 following SARS-CoV-2 infection remains difficult. Severe inflammatory reactions and thrombotic complications (blood clots) in particular can be life-threatening. Classic anticoagulants ...
Aug 16, 2024
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A multicenter safety study at UC Davis Health tested a protein drug (INBRX-101), developed to improve care for people with alpha-1 antitrypsin deficiency (AATD), and showed the therapy is quite safe.
Jul 11, 2024
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Diabetic kidney disease (DKD) is a major microvascular complication of type 2 diabetes mellitus (T2DM), causing irreversible kidney damage and poor prognosis for patients. Early monitoring and screening of renal injury are ...
Jul 19, 2023
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In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that ...
Jul 25, 2022
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