January 15, 2010

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Superior mesenteric artery syndrome in a diabetic patient

Diabetes mellitus is one of the most common chronic disease of the world and the prevalence of diabetes mellitus is over 10% in Taiwan. Gastroparesis is reported in 5% to 12% of diabetic patients. Superior mesenteric artery (SMA) syndrome is an uncommon disease resulting compression of the third portion of the duodenum from the superior mesenteric artery. However, SMA syndrome can cause the same symptoms as diabetic gastroparesis.

A research team, led by Dr. Wen-Ming Wang from Kaohsiung Medical University Hospital reported a rare etiology of superior mesenteric artery syndrome. Their study will be published on December 21, 2009 in the World Journal of Gastroenterology.

Their report suggest that diabetic patients with gastrointestinal symptoms and bodyweight loss should be considered for SMA syndrome, despite the gastroparesis is the most common etiology. Computed tomography and upper gastrointestinal series are the reliable tools for diagnosis. Adequate nutrition supply is a useful treatment and the aim is bodyweight gain and symptom relief. Surgery is indicated when conservative treatment fails.

More information: Wu MC, Wu IC, Wu JY, Wu DC, Wang WM. Superior mesenteric artery syndrome in a diabetic patient with acute weight loss. World J Gastroenterol 2009; 15(47): 6004-6006 www.wjgnet.com/1007-9327/15/6004.asp

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