Teens with autism more likely to develop type 2 diabetes

March 28, 2016

(HealthDay)—Adolescents and young adults with autism spectrum disorder (ASD) are more likely to develop type 2 diabetes mellitus (T2DM), according to a study published online March 22 in Diabetes Care.

Mu-Hong Chen, M.D., from the Taipei Veterans General Hospital in Taiwan, and colleagues used the Taiwan National Health Insurance Research Database to identify 6,122 adolescents and young adults with ASD and 24,488 age- and sex-matched control subjects (2002 to 2009). Patients were monitored until the end of 2011 to identify those who developed T2DM.

The researchers found that adolescents (hazard ratio [HR], 2.71) and (HR, 5.31) with ASD had a higher risk of developing T2DM versus those without ASD, after adjusting for demographic data, use of atypical antipsychotic, and medical comorbidities. There was also a higher likelihood of subsequent T2DM tied to short-term (HR, 1.97) and long-term (HR, 1.64) use of atypical antipsychotics.

"Further research is necessary to investigate the common pathophysiology of ASD and T2DM," the authors write.

Explore further: Off-label use of metformin common in U.S. adolescents

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Off-label use of metformin common in U.S. adolescents

March 15, 2016
(HealthDay)—In U.S. adolescents, off-label use of metformin is common, according to a study published online March 9 in the Journal of Clinical Pharmacy and Therapeutics.

NAFLD linked to unfavorable metabolic profile in T2DM

February 17, 2016
(HealthDay)—For obese patients with type 2 diabetes mellitus (T2DM), nonalcoholic fatty liver disease (NAFLD) is associated with an unfavorable metabolic profile, according to a study published online Feb. 9 in Diabetes ...

Long-term post-CABG mortality increased with diabetes

April 30, 2015
(HealthDay)—Patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) have increased long-term risk of death after coronary artery bypass grafting (CABG), with higher risk among those with T1DM, ...

Intra-pancreatic triacylglycerol drops with weight loss in T2DM

December 21, 2015
(HealthDay)—The weight loss-associated decrease in intra-pancreatic triacylglycerol which occurs after gastric bypass is specific to type 2 diabetes mellitus (T2DM), according to a study published online Dec. 1 in Diabetes ...

Animal-source, low-carb diet ups T2DM risk with past GDM

November 25, 2015
(HealthDay)—For women with a history of gestational diabetes mellitus (GDM), a low-carbohydrate diet (LCD), particularly one from animal-source foods, is associated with increased risk of type 2 diabetes mellitus (T2DM), ...

Reduction in proximal, distal leg muscle strength in T2DM

January 11, 2016
(HealthDay)—For patients with type 2 diabetes mellitus (T2DM), proximal and distal leg muscle strength is reduced, and proximal but not distal muscle volume is also reduced, according to a study published online Jan. 6 ...

Recommended for you

Consuming low-calorie sweeteners may predispose overweight individuals to diabetes

March 18, 2018
Consumption of low-calorie sweeteners could promote metabolic syndrome and predispose people to prediabetes and diabetes, particularly in individuals with obesity, a new study on human fat-derived stem cells and fat samples ...

Are high blood glucose levels an effect rather than the cause of diabetes?

March 15, 2018
Insulin resistance and elevated blood glucose levels are considered to be the cause of type 2 diabetes. However, scientists from the German Cancer Research Center (DKFZ) and Heidelberg University Hospital have now provided ...

Smoking linked with higher risk of type 2 diabetes

March 15, 2018
The prevalence of diabetes has increased almost 10-fold in China since the early 1980s, with one in 10 adults in China now affected by diabetes. Although adiposity is the major modifiable risk factor for diabetes, other research ...

Social support and machine learning are at the core of a student-developed app for people with diabetes

March 14, 2018
Diabetes is the seventh leading cause of death in the U.S., and nearly 10 percent of the population suffers from this chronic disease, according to the Centers for Disease Control and Prevention.

Toxic proteins and type 2 diabetes

March 9, 2018
Nearly a half-billion people worldwide live with type 2 diabetes. Yet despite the disease's sizeable and increasing impact, its precise causes remain murky. Current scientific thinking points to two key processes: insulin ...

Fiber-fermenting bacteria improve health of type 2 diabetes patients

March 8, 2018
The fight against type 2 diabetes may soon improve thanks to a pioneering high-fiber diet study led by a Rutgers University-New Brunswick professor.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.